Thanks, firstly, to Greg Tyrelle for supplying a working parser example. I believe I've "got it" now... Later today I'll be uploading the working (though minimal and still sloppily written) ESearch module components to my "point-n-laugh" section. Following that, I'll work on getting the XML parser and interface for POST'ing queries to webservers more properly separated and abstracted out for "semi-official" release. Once that's done, the more detailed work to get minimal useful ESummary and EFetch modules working should not require much additional labor. After that I'll be getting back to the NCBI Blast interface (which you can find a more-or-less working unrefined version of in the "point-n-laugh" section, which is effectively capable of submitting a sequence and parameters for a sequence query, and more-or-less properly waiting for the results to come back. It just doesn't do any PARSING of the results at all...) A sort of "personal milestone" that I'm aiming for is to be able to put together an example "tell me about this sequence" application, which would examine results of an NCBI Blast query and, using information pulled from the closest matches that turn up, report things like probable taxonomic classification, type of sequence, and pointers to likely-related pubmed articles, and so on. As always, comments and suggestions are welcome. Thanks.