Sean, Thanks for the quick update. I hate to disturb you in your "coding frenzy", but I have some Perl/BioPerl scripts that I'm interfacing with PHP. Could you check if bioinformatics.org allows installation of said scripts? As for PROSITE, yes, it appears they do not have such a facility/service for returning query results in XML. Thanks! Regards, Serge Need a new email address that people can remember Check out the new EudoraMail at http://www.eudoramail.com