Hi Marko. The binaries for the version on the MeltSim website, were compiled with Delphi 2 on Windows 98. Quite a bit has changed since then, especially, I imagine, multi-lingual interfaces for Windows. I think the problem *may* be resolved by recompiling MeltSim using a recent version of Delphi, maybe even on the German version of XP. The source code for MeltSim/Windows is available: http://bioinformatics.org/ftp/meltsim/meltsim-win-1-0b2-source.tar.gz And I think you can get the trial version of Delphi for free: http://borland.com/products/downloads/download_delphi.html# Taofiq Paraiso <tao at nordita.dk> (CC'd) mentioned that he recently recompiled MeltSim. You may want to ask him for the binaries to see if they work any better. Cheers. Jeff Marko Pavlekovic wrote: > > I would like to use MeltSim Program, but unfortunately it does not work. > I get all kind of error messages. I am using Win XP SP2 german version. > > Opening a file in MELT containing nothing else but the sequence seems to > work. But letting the program do its calculation it fails with the > following error message: “Exception EconvertError in module MELT.exe at > 00004A62. ´0.075´is not a valid floating piont value.” Now changing all > “*.*” in “Starting Temp.”, “Final Temp.”, “Temperature Increment” and > “Sodium Molarity” to “*,*” works and the program does the calculation. > At the end of the calculation the program creates four files: *.log, > *.mtl, *.pos and *.pro. Trying to open the files with GRAPH failes unles > I change all “.” in these files to “,”. After this GRAPH can read some > of these files. Nevertheless, the graph looks completely strange and I > still cannot open one file: *.pos. > > Does anyone know a possible solution for this problem???? -- J.W. Bizzaro Bioinformatics Organization, Inc. (Bioinformatics.Org) E-mail: jeff at bioinformatics.org Phone: +1 508 890 8600 --