[meltsim] difference plot in meltsim?

J.W. Bizzaro jeff at bioinformatics.org
Tue Aug 21 16:37:44 EDT 2007

Hi Kevin,

Are you asking about a plot of the difference between two melting curves (derivative profile, positional map, or positional profile?) or something else?


Kevin Hollevoet wrote:
> hello,
> i was wondering i you have within melstim any simulation option that can 
> generate the difference plots? i think it is possible if i do it with 
> the log data from different data in excel or some other program, but 
> that is obviously quite some work.
> so simulation of some difference plot to show the possible clustering 
> would be very attractive to us. because we are trying to show that HRM 
> analysis of heterogene methylated NB cellines is not possible. in other 
> words that the clustering would be insignificant to give some idea about 
> the methylation status.
> could you give me a hint here?
> thank you,
> kevin

J.W. Bizzaro
Bioinformatics Organization, Inc. (Bioinformatics.Org)
E-mail: jeff at bioinformatics.org
Phone:  +1 508 890 8600

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