[MeltSim] Question about strand concentration
richard blake
doug8829 at roadrunner.com
Fri Mar 26 15:56:07 EDT 2010
Strand concentrations are important only for short DNAs, of for DNA
strands interacting with oligonucleotides. The effects of
concentration are nil for DNAs longer than about 20-mers. The
literature on the effects of concentration is ancient, perhaps fifty
years old, but it is what some of us cut our teeth on.
On Mar 25, 2010, at 12:06 PM, Zachary L Dwight wrote:
> Is strand concentration not included as a parameter because the
> range of concentrations most likely being used would have no effect
> on the TM? Thanks so much,
>
> Zach Dwight
> Univ of Utah
> Dept of Pathology
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> MeltSim maillist - MeltSim at bioinformatics.org
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