[MeltSim] Question about strand concentration

richard blake doug8829 at roadrunner.com
Fri Mar 26 15:56:07 EDT 2010

Strand concentrations are important only for short DNAs, of for DNA  
strands interacting with oligonucleotides. The effects of  
concentration are nil for DNAs longer than about 20-mers. The  
literature on the effects of concentration is ancient, perhaps fifty  
years old, but it is what some of us cut our teeth on.
On Mar 25, 2010, at 12:06 PM, Zachary L Dwight wrote:

> Is strand concentration not included as a parameter because the  
> range of concentrations most likely being used would have no effect  
> on the TM?  Thanks so much,
> Zach Dwight
> Univ of Utah
> Dept of Pathology
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> MeltSim maillist  -  MeltSim at bioinformatics.org
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