[MeltSim] Question about strand concentration

[Marx, Kenneth]

Hi Dick,
 
The literature's so old, I'm not sure I 've even seen papers on this. Good to hear from you. Hope things are going well.
 
Regards, Ken

________________________________

From: meltsim-bounces at bioinformatics.org on behalf of richard blake
Sent: Fri 3/26/2010 3:56 PM
To: General discussions about MeltSim
Subject: Re: [MeltSim] Question about strand concentration



Strand concentrations are important only for short DNAs, of for DNA 
strands interacting with oligonucleotides. The effects of 
concentration are nil for DNAs longer than about 20-mers. The 
literature on the effects of concentration is ancient, perhaps fifty 
years old, but it is what some of us cut our teeth on.
On Mar 25, 2010, at 12:06 PM, Zachary L Dwight wrote:

> Is strand concentration not included as a parameter because the 
> range of concentrations most likely being used would have no effect 
> on the TM?  Thanks so much,
>
> Zach Dwight
> Univ of Utah
> Dept of Pathology
> _______________________________________________
> MeltSim maillist  -  MeltSim at bioinformatics.org
> http://www.bioinformatics.org/mailman/listinfo/meltsim


_______________________________________________
MeltSim maillist  -  MeltSim at bioinformatics.org
http://www.bioinformatics.org/mailman/listinfo/meltsim


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