Hello, I'm Humberto Ortiz-Zuazaga, I work with the University of Puerto Rico's Institute of Neurobiology: http://www.neurobio.upr.clu.edu/ I've been given the go ahead to develop sequence analysis tools for a molecular biology core facility being set up here. I'd like to contribute to the Loci project, as it looks like you've designed the very system I'd like to create (by the way, where is the design document? I read it friday night, but it's not on the new web site yet). I've got a couple of years experience developing sequence analysis and genetic mapping tools, some of which are available on the web: http://www-bio.cnnet.clu.edu/analysis/ (when it's up) http://www.neurobio.upr.clu.edu/~hortiz/cmb/tkmap/ http://www.neurobio.upr.clu.edu/~hortiz/cmb/bpe/ I've dabbled a little in python, and done no gnome programming, but I agree with both these choices for a analysis GUI. I've gotten the python-gnome package set up on my machine, and looked over the mailing list archives (and subscribed). I look forward to contributing. -- Humberto Ortiz Zuazaga Bioinformatics Specialist Institute of Neurobiology hortiz at neurobio.upr.clu.edu