From Bioinformatics.Org Wiki
CyNote aims to be a electronic research record management system that conforms to record-keeping standards of physical notebooks based on 3 principles:
1. Notebooks can be setup for encryption and routine backup on secured data centres (such as Amazon S3)
2. Date-time stamping of notebooks are performed by remote systems (immediate date-time stamp upon upload)
3. Page edits are generally disallowed (in conformance to US FDA 21 CFR Part 11's Rules on Electronic Records). However, if page edits are forcefully done, it will be tracked and date-time stamped using source code management systems (such as Subversion)
At the same time, research tools can be developed as plugins into CyNote and records can be tracked immediately; thus, saving the effort in transposing data across systems.