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A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species Russell Bell1., Alan Hubbard2,3., Rakesh Chettier1., Di Chen3, John P. Miller3, Pankaj Kapahi3, Mark Tarnopolsky4, Sudhir Sahasrabuhde1, Simon Melov3, Robert E. Hughes3*

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Molecular Systems Biology 3; Article number 89; doi:10.1038/msb4100134 Citation: Molecular Systems Biology 3: 89 & 2007 EMBO and Nature Publishing Group All rights reserved 1744-4292/07 www.molecularsystemsbiology.com Large-scale mapping of human protein–protein interactions by mass spectrometry