Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
BAK1BCL2-antagonist/killer 1Adaptor ProteinSelf-Sufficiency in Growth SignalCell GrowthmiR-125b mediated suppression of BAK1 results in androgen independent growth of prostate cancer cellsReference
BAK1BCL2-antagonist/killer 1Adaptor ProteinCell Death ResistanceApoptosis EvasionBAK1 is a proapoptotic regulator and is inhibited by the miR-125b which functions as an oncogene in prostate cancerReference
BAK1BCL2-antagonist/killer 1Adaptor ProteinCell Death ResistanceApoptosis EvasionEndothelin1 decreased the expression of BAK1 in prostate cancerReference

Back