| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| DVL2 | Dishevelled segment polarity protein 2 | Adaptor Protein | Self-Sufficiency in Growth Signal | Cell Growth | Enhances prostate cancer growth potential by up regulating AR expression in androgen dependent prostate cancer cell line. | Reference |
| DVL2 | Dishevelled segment polarity protein 2 | Adaptor Protein | Metastasis | Cell Invasion | Silencing of DVL2 expression decrease cell proliferation, motility , Cell Invasion and Wnt-3a, AR, MMP-2, MMP-9 expression in LNCaP prostate cancer cell | Reference |
| DVL2 | Dishevelled segment polarity protein 2 | Adaptor Protein | Metastasis | Cell Motility | Critically involved in prostate cancer cell motility, regulates AR,MMP2,MMP9 expression. | Reference |
| DVL2 | Dishevelled segment polarity protein 2 | Adaptor Protein | Metastasis | Cell Migration | Involves in androgen independent prostate cancer cell migration and its activity is regulated by miR-221 | Reference |
| DVL2 | Dishevelled segment polarity protein 2 | Adaptor Protein | Metastasis | Cell Proliferation | Silencing of DVL2 expression decrease cell proliferation, motility , Cell Invasion and Wnt-3a, AR, MMP-2, MMP-9 expression in LNCaP prostate cancer cell | Reference |
| DVL2 | Dishevelled segment polarity protein 2 | Adaptor Protein | Insensitivity to Anti-Growth Signal | Cell Cycle | DVL2 plays a role in G1 to S phase transition of prostate cancer cell cycle by targeting cyclin D1 through KIF3a-DVL2-?-catenin axis. | Reference |