Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
TRADDTNFRSF1A-associated via death domainAdaptor ProteinCell Death ResistanceAoptosis Resistanceandrogen change the TRADD/RIP1 ratio, which results in the NF-kappaB activation and sequentially blocks TRAIL-induced apoptosis mechineryReference
TRADDTNFRSF1A-associated via death domainAdaptor ProteinCell Death ResistanceAoptosis ResistanceAndrogen deprivation therapy results in the rising of TNF-alpha resistance by reducing TRADD expression during prostate cancer developmentReference

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