| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| CFLAR | CASP8 and FADD-like apoptosis regulator | Adaptor Protein | Self-Sufficiency in Growth Signal | Cell Survival | Androgen recptor regulates CFLAR and effects prostate cancer cell survival | Reference |
| CFLAR | CASP8 and FADD-like apoptosis regulator | Adaptor Protein | Metastasis | Metastasis | CFLAR is involved in prostate cancer metastasis by blocking proteasome mediated degradation of betacatenine | Reference |
| CFLAR | CASP8 and FADD-like apoptosis regulator | Adaptor Protein | Cell Death Resistance | Aoptosis Resistance | It is directly targeted by AR and is involved in regulation of Fas/FasL mediated apoptosis: plays a role in apoptosis inhibition in androgen dependent prostate cancer cell line. | Reference |
| CFLAR | CASP8 and FADD-like apoptosis regulator | Adaptor Protein | Cell Death Resistance | Aoptosis Resistance | It functions as a key regulator of androgen deprivation therapy response & mediates castration resistance: confers resistance of metastatic CaP cells to docetaxel, TRAIL, and oxaliplatin. | Reference |