Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
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EPHB2 | EPH receptor B2 | Receptor Tyrosine Kinase | Insensitivity to Anti-Growth Signal | Tumor Suppression | EPHB2 is implicated as a prostate cancer tumour suppressor gene with somatic inactivating mutations occurring in ?10% of sporadic prostatic tumours. | Reference |
EPHB2 | EPH receptor B2 | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | EPHB2 play an important roles in Prostate cancer cell growth as its transfection in DU 145 cells which lack the EPHB2 suppresses clonogenic growth. | Reference |
EPHB2 | EPH receptor B2 | Receptor Tyrosine Kinase | Genome Instability, Mutation & Perturbation | Mutation | Frameshift, splice site, missense and nonsense mutations are found in the EPHB2 gene in clinical prostate cancer samples. | Reference |