| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Tumour Microenvironment | Cancer Microenvironment | In the hypoxic tumour microenvironment and bone microenvironment, enhanced GAS6/Axl signaling drives prostate tumorigenesis. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Survival | AXL is involved in prostate cancer cell survival as suppression of AXL by small interfering RNA suppress prostate cancer cell survival. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | AXL is an important regulator of prostate cancer cell growth as inhibition of AXL gene expression results in suppression of prostate cancer cell growth. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Proliferation | AXL is an important regulator of prostate cancer cell proliferation as inhibition of AXL gene expression results in suppression of prostate cancer cell proliferation. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Metastasis | Metastasis | AXL and its receptor GAS6 play an important role in human prostate cancer metastasis, supported by experiments on PC3 and DU145 prostate cancer cells. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Metastasis | Cell Invasion | AXL and its receptor GAS6 are involved in prostate cancer cell invasion in PC3 and DU145 prostate cancer cells. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Metastasis | Epithelial Mesenchymal Transition(EMT) | AXL regulates epithelial mesenchymal (EMT) marker expression in prostate cancer, supported by experiments on PC3 and DU145 prostate cancer cells. | Reference |
| AXL | AXL receptor tyrosine kinase | Receptor Tyrosine Kinase | Metastasis | Cell Migration | AXL and its receptor GAS6 are involved in prostate cancer cell migration in PC3 and DU145 prostate cancer cells. | Reference |