| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| PHB | Prohibitin | Adaptor Protein | Insensitivity to Anti-Growth Signal | Tumor Suppression | PHB acts as a tumour suppressor and AR co repressor in prostate cancer; It is targeted by miR-27a, which is regulated by AR. | Reference |
| PHB | Prohibitin | Adaptor Protein | Insensitivity to Anti-Growth Signal | Tumor Suppression | PHB mediates tumour suppressive effects in prostate cancer and is involved in maintaining a balance between cell survival and apoptosis | Reference |
| PHB | Prohibitin | Adaptor Protein | Insensitivity to Anti-Growth Signal | Cell Cycle | Prohibitin(PHB) has a nuclear regulatory role in prostate cancer. | Reference |
| PHB | Prohibitin | Adaptor Protein | Self-Sufficiency in Growth Signal | Cell Growth | Prohibitin(PHB) is down regulated by androgen and enhances androgen stimulated growth and cell cycle entry in prostate cancer. | Reference |
| PHB | Prohibitin | Adaptor Protein | Metastasis | Cell Proliferation | Prohibitin(PHB), a cell cycle regulatory protein is involved in prostate cancer cell proliferation in an androgen receptor dependent manner in LNCaP cells. | Reference |
| PHB | Prohibitin | Adaptor Protein | Cell Death Resistance | Aoptosis Resistance | Prohibitin(PHB) is involved in TGF beta mediated apoptosis in prostate cancer cell in both Smad dependent and Smad independent way. | Reference |