| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| PDGFRA | Platelet-derived growth factor receptor, alpha polypeptide | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Survival | PDGFRA is implicated in prostate cancer cell survival. | Reference |
| PDGFRA | Platelet-derived growth factor receptor, alpha polypeptide | Receptor Tyrosine Kinase | Angiogenesis | Angiogenesis | PDGFRA is involved in prostate cancer angiogenesis as in prostate cancer xenograft mice treated with siPDGFRA shows a significant decrease in microvessel density. | Reference |
| PDGFRA | Platelet-derived growth factor receptor, alpha polypeptide | Receptor Tyrosine Kinase | Metastasis | Bone Metastasis | PDGFRA is involved in prostate cancer bone metastasis as the bone marrow activates PDGFRalpha in a ligand-independent fashion. | Reference |
| PDGFRA | Platelet-derived growth factor receptor, alpha polypeptide | Receptor Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Survival | Mediates prostate cancer cell survival through Akt/PKB manner in bone metastatic prostate cancer. | Reference |
| PDGFRA | Platelet-derived growth factor receptor, alpha polypeptide | Receptor Tyrosine Kinase | Metastasis | Bone Metastasis | It is involved in stronger activation of the Akt/PKB survival pathway in bone-metastatic prostate cancer cells. | Reference |