| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| PRKCA | Protein kinase C, alpha | Serine/Threonine Kinase | Angiogenesis | Angiogenesis | Protein kinase C alpha (PKCA) is involved in prostate cancer angiogenesis through PKCalpha/c-Src/IKK/NF-kappaB signaling cascades leading to COX-2-mediated PGE2 production and MMP-2 activation in PC-3 xenograft model. | Reference |
| PRKCA | Protein kinase C, alpha | Serine/Threonine Kinase | Metastasis | Cell Invasion | Protein kinase C alpha (PKCA) is associated with prostate cancer cell invasion in an androgen responsive way. | Reference |
| PRKCA | Protein kinase C, alpha | Serine/Threonine Kinase | Cell Death Resistance | Chemoresistance | It plays a role in the development of cisplatin resistance through stabilization of BCL2 in both androgen dependent & independent prostate cancer cell line. | Reference |
| PRKCA | Protein kinase C, alpha | Serine/Threonine Kinase | Enabling Replicative Immortality | Telomere maintenance | PRKCA plays a significant role in human prostate cancer by mediating posttranslational modification telomerase reverse transcriptase (hTERT) and there by promoting its nulear translocation. | Reference |