Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
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MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Self-Sufficiency in Growth Signal | Cell Survival | MAPK3(ERK1) is associated with prostate cancer cell survival through PKCepsilon/PKD3 pathway. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | MAPK3(ERK1) is associated with prostate cancer cell growth through PKCepsilon/PKD3 pathway. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Self-Sufficiency in Growth Signal | Cell Proliferation | MAPK3(ERK1) activation through PI3K mediated signaling play an important role in prostate cancer cell proliferation. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Angiogenesis | Angiogenesis | MAPK3 is involved in prostate cancer angiogenesis in response of osteopontin/alphavbeta3 signaling pathway and mediates the expression of VEGF in androgen independent prostate cancer cell line. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Angiogenesis | Angiogenesis | miR-21 induces prostate cancer angiogenesis through activation of ERK1/2 mediated signaling and enhancing HIF-1alpha and VEGF expression. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Metastasis | Cell Invasion | MAPK3(ERK1) activation is an important step in CXCL13-mediated prostate cancer cell invasion. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Metastasis | Cell Invasion | MAPK3(ERK1) phosphorylation in response of human chorionic gonadotropin beta (hCGbeta) is associated with prostate cancer cell invasion. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Metastasis | Cell Motility | MAPK3(ERK1) phosphorylation in response of human chorionic gonadotropin beta (hCGbeta) is associated with prostate cancer cell motility. | Reference |
MAPK3 | Mitogen-activated protein kinase 3 | Serine/Threonine Kinase | Metastasis | Cell Migration | MAPK3(ERK1) phosphorylation in response of human chorionic gonadotropin beta (hCGbeta) is associated with prostate cancer cell migration. | Reference |