Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
---|
RAF1 | V-raf-1 murine leukemia viral oncogene homolog 1 | Serine/Threonine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | RAF1 play an important role in growth suppresion of prostate cancer through RAF/MEK/MAPK pathway activation. | Reference |
RAF1 | V-raf-1 murine leukemia viral oncogene homolog 1 | Serine/Threonine Kinase | Genome Instability, Mutation & Perturbation | Gene Amplification | Activation of the RAS/RAF/MEK/ERK pathway play an important role in prostate cancer development along with RAF gene copy number gain. | Reference |
RAF1 | V-raf-1 murine leukemia viral oncogene homolog 1 | Serine/Threonine Kinase | Genome Instability, Mutation & Perturbation | Gene Amplification | Gene amplification of RAF1 occur much more frequently during progression from hormone-sensitive to hormone-resistant cancer. | Reference |