Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
CDK5Cyclin-dependent kinase 5Serine/Threonine KinaseSelf-Sufficiency in Growth SignalCell GrowthCDK5 plays a role in prostate cancer cell growth by regulating androgen receptor stability.Reference
CDK5Cyclin-dependent kinase 5Serine/Threonine KinaseMetastasisMetastasisCDK5 regulates the metastatic potential of prostate cancer by influencing many steps associated with metastasis.Reference
CDK5Cyclin-dependent kinase 5Serine/Threonine KinaseMetastasisCell MotilityCDK5 is involved in the regulation of prostate cancer cell motility.Reference
CDK5Cyclin-dependent kinase 5Serine/Threonine KinaseAndrogen Receptor SignallingAR SignalingCyclin-dependent kinase 5 (Cdk5) critically modulates androgen receptor (AR) mediated signaling and there by promotes human prostate cancer cell growth.Reference

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