| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| JAK2 | Janus kinase 2 | Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | JAK2 is involved in both primary and castration resistant prostate cancer cell growth through JAK2-STAT5 mediated signaling as JAK2 inhibitor suppress both types of prostate cancer cell growth. | Reference |
| JAK2 | Janus kinase 2 | Tyrosine Kinase | Metastasis | Cell Motility | JAK2 is involved in prostate cancer cell motility through JAK2-STAT3 mediated signaling as JAK2 inhibition results in reduced activation of STAT3 and suppression of prostate cancer cell motility. | Reference |
| JAK2 | Janus kinase 2 | Tyrosine Kinase | Metastasis | Epithelial Mesenchymal Transition(EMT) | JAK2-STAT5a/b mediated signaling plays a role in prostate cancer epithelial mesenchymal transition. | Reference |