Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
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FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Insensitivity to Anti-Growth Signal | Tumor Suppression | FYN functions as a prostate cancer tumour suppressor in the altered biochemical landscape of neoplastic transformation. | Reference |
FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Insensitivity to Anti-Growth Signal | Tumor Suppression | FYN located at chromosome 6q21 play a tumour suppressive role during prostate cancer progression; suffers from chromosomal deletion & promoter hypermethylation.. | Reference |
FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Growth | FYN play an important role in prostate cancer cell growth mediated by HGF/MET signaling axis. | Reference |
FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Self-Sufficiency in Growth Signal | Cell Proliferation | FYN is involved in the prostate cancer cell proliferation through both integrin and receptor tyrosine kinase mediated manner. | Reference |
FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Genome Instability, Mutation & Perturbation | Genome Instability | FYN is downregulated in prostate cancer by both chromosomal deletion and promoter hypermethylation, and therefore is a novel prostate tumor suppressor gene candidate. | Reference |
FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Genome Instability, Mutation & Perturbation | Overexpression | FYN is overexpressed during prostate cancer progression. | Reference |
FYN | FYN oncogene related to SRC, FGR, YES | Tyrosine Kinase | Metastasis | Cell Motility | FYN is involved in the prostate cancer cell motility through both integrin and receptor tyrosine kinase mediated manner. | Reference |