| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|
| MED12 | Mediator complex subunit 12 | Transcription Regulatory Protein | Insensitivity to Anti-Growth Signal | Cell Cycle | MED12, overexpressed in castration resistant prostate cancer and plays a role in G1 to S phase cell cycle transition. | Reference |
| MED12 | Mediator complex subunit 12 | Transcription Regulatory Protein | Castration Resistance | Castration Resistance | MED12, which encodes a subunit of the Mediator complex, is overexpressed in CRPC, is involved in the progression of castration resistant prostate cancer (CRPC) in a TGF-beta dependent manner. | Reference |
| MED12 | Mediator complex subunit 12 | Transcription Regulatory Protein | Genome Instability, Mutation & Perturbation | Mutation | Somatic mutation is present in exon 26 of MED12 (Mediator complex subunit 12) and plays an important role in prostate tumorigenesis. | Reference |