Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
CDK6Cyclin-dependent kinase 6Cell Cycle Control ProteinInsensitivity to Anti-Growth SignalCell CycleCyclin-dependent kinase 6 (CDK6) is associated with G1 to S phase transition of prostate cancer cell cycle through enhancement of androgen receptor activity.Reference
CDK6Cyclin-dependent kinase 6Cell Cycle Control ProteinMetastasisBone MetastasisCell cycle regulator cycline dependent kinase 6 (CDK6) is significantly involved with prostate cancer bone metastasis associated dormancy escape mechanisms through activation of cell proliferation and cell cycle progression.Reference

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