Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
SREBP1Sterol regulatory element binding transcription factor 1Transcription FactorCastration ResistanceCastration ResistanceSterol regulatory element-binding protein-1 (SREBP-1) plays a pivotal role in the promotion of castration resistant prostate cancer (CRPC) through activation of androgen receptor(AR) and modulation of lipogenesis and ROS signaling.Reference

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