| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| PKIB | Protein kinase (cAMP-dependent, catalytic) inhibitor beta | Enzyme Regulator | Castration Resistance | Castration Resistance | PKIB (cAMP-dependent protein kinase inhibitor-beta), which was overexpressed specifically in CRPC, plays a vital role in aggressive manifestation of castration resistant prostate cancer (CRPC) through AKT phosphorylation. | Reference |