Human Prostrate Cancer Hallmarks Map



ProteinProtein NameMolecular TypeHallmarkFeatureEvidenceReference
CUL1Cullin 1Ubiquitin proteasome system proteinSelf-Sufficiency in Growth SignalCell ProliferationCullin-1 (CUL1), which is highly expressed in human prostate cancer, is involved in prostate cancer associated cell proliferation through regulation of cell cycle.Reference
CUL1Cullin 1Ubiquitin proteasome system proteinInsensitivity to Anti-Growth SignalCell CycleCullin-1 (CUL1), which is highly expressed in human prostate cancer, is involved in prostate cancer associated cell proliferation through regulation of cell cycle by regulating the expression of cyclin D, cyclin E, p21 and p27.Reference

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