| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| KLK2 | kallikrein related peptidase 2 | Serine Protease | Androgen Independence | Androgen Independence | Kallikrein related peptidase 2 (KLK2) plays an important modulatory role in the transactivation of androgen receptor (AR), which enhances prostate cancer cell growth and there by promotes human prostate tumorigenesis (outlaw activation). | Reference |
| KLK2 | kallikrein related peptidase 2 | Serine Protease | Genome Instability, Mutation & Perturbation | Genome Instability | SPOP gene mutation drives human prostate cancer development through genomic instability via modulation of DNA double strand break (DSB) repair. | Reference |