| Protein | Protein Name | Molecular Type | Hallmark | Feature | Evidence | Reference |
|---|---|---|---|---|---|---|
| IGFBP5 | Insulin like growth factor binding protein 5 | Adhesion Molecule | Metastasis | Bone Metastasis | Insulin-like growth factor binding protein 5 (IGFBP-5), a osteoclastogenic factor is secreted from both osteolytic prostate cancer cells and osteoblasts in prostate cancer bone microenvironment and induces osteoclastogenesis, osteoblast proliferation and signaling. | Reference |