[BiO BB] About clustering genes to gene family

[Joel Dudley]

Carol,
  This site may provide some useful information for you:

http://pbil.univ-lyon1.fr/databases/hovergen.html

Joel Dudley
Faculty Research Associate
Arizona State University
Center for Evolutionary and Functional Genomics
http://lsweb.la.asu.edu/skumar/


-----Original Message-----
From: Zheng Fu [mailto:zfu at cs.ucr.edu]
Sent: Thursday, August 07, 2003 10:38 AM
To: bio_bulletin_board at bioinformatics.org
Subject: [BiO BB] About clustering genes to gene family


Hi everyone,

Does anyone know how to clustering genes to a gene family based on the
sequence alignments.
For two genes, we can define a threshold to seperate the homolog and
non-homolog. But for three or more genes,how to define the homologs?(Such
as Gene A and Gene B has high alignment score, A and C also has high sore,
but B and C doesn't have high socre, can we say ABC are homologs?

Thank you.

Carol

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