Basic Information
Gene ID 100054693
Gene Name STAT4
Full Name Signal transducer and activator of transcription
Organism Equus caballus [9796]

Cross Reference
UniProt F7CJM0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSECAP00000021075 Gene3D G3DSA:1.10.238.10 IPR011992 457 577 1.40e-49 EF-hand domain pair
ENSECAP00000021075 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 3.50e-45 STAT transcription factor, protein interaction
ENSECAP00000021075 Gene3D G3DSA:1.20.1050.20 IPR013800 138 316 1.00e-63 STAT transcription factor, all-alpha
ENSECAP00000021075 Gene3D G3DSA:2.60.40.630 IPR012345 317 456 2.80e-57 STAT transcription factor, DNA-binding, subdomain
ENSECAP00000021075 Gene3D G3DSA:3.30.505.10 IPR000980 578 703 6.60e-50 SH2 domain
ENSECAP00000021075 PANTHER PTHR11801 IPR001217 2 741 0.00e-00 Transcription factor STAT
ENSECAP00000021075 Pfam PF00017 IPR000980 573 627 2.60e-11 SH2 domain
ENSECAP00000021075 Pfam PF01017 IPR013800 137 314 1.80e-64 STAT transcription factor, all-alpha
ENSECAP00000021075 Pfam PF02864 IPR013801 316 563 4.00e-113 STAT transcription factor, DNA-binding
ENSECAP00000021075 Pfam PF02865 IPR013799 2 121 1.80e-42 STAT transcription factor, protein interaction
ENSECAP00000021075 ProSiteProfiles PS50001 IPR000980 569 647 0.00e-00 SH2 domain
ENSECAP00000021075 SMART SM00252 IPR000980 571 681 5.70e-03 SH2 domain
ENSECAP00000021075 SMART SM00964 IPR013799 2 122 7.70e-66 STAT transcription factor, protein interaction
ENSECAP00000021075 SUPERFAMILY SSF47655 IPR015988 136 316 0.00e-00 STAT transcription factor, coiled coil
ENSECAP00000021075 SUPERFAMILY SSF48092 IPR013799 1 121 0.00e-00 STAT transcription factor, protein interaction
ENSECAP00000021075 SUPERFAMILY SSF49417 IPR008967 316 564 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSECAP00000021075 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSECAP00000021075 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSECAP00000021075 PF02865 1.80067e-42 STAT_int STAT protein, protein interaction domain
ENSECAP00000021075 PF00017 4e-12 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSECAP00000021075 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSECAP00000021075 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSECAP00000021075 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSECAP00000021075 GO:0005634 cellular_component nucleus
ENSECAP00000021075 GO:0005737 cellular_component cytoplasm
ENSECAP00000021075 GO:0003677 molecular_function DNA binding
ENSECAP00000021075 GO:0004871 molecular_function signal transducer activity
ENSECAP00000021075 GO:0005509 molecular_function calcium ion binding
ENSECAP00000021075 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100402355 10029 Cricetulus griseus 100769249
9597 Pan paniscus 100972895 9555 Papio anubis 101007479
39432 Saimiri boliviensis 101030273 31033 Takifugu rubripes 101068057
10090 Mus musculus 20849 9606 Homo sapiens 6775
9358 Choloepus hoffmanni ENSCHOG00000006838 10020 Dipodomys ordii ENSDORG00000011535
9365 Erinaceus europaeus ENSEEUG00000002778 9371 Echinops telfairi ENSETEG00000017045
9685 Felis catus ENSFCAG00000018634 69293 Gasterosteus aculeatus ENSGACG00000002684
9031 Gallus gallus ENSGALG00000025974 8049 Gadus morhua ENSGMOG00000008284
9785 Loxodonta africana ENSLAFG00000012299 9315 Macropus eugenii ENSMEUG00000016504
30608 Microcebus murinus ENSMICG00000002951 9544 Macaca mulatta ENSMMUG00000005617
9669 Mustela putorius furo ENSMPUG00000012539 9258 Ornithorhynchus anatinus ENSOANG00000022251
30611 Otolemur garnettii ENSOGAG00000003042 8128 Oreochromis niloticus ENSONIG00000016817
9978 Ochotona princeps ENSOPRG00000008636 8090 Oryzias latipes ENSORLG00000015180
9813 Procavia capensis ENSPCAG00000006029 9601 Pongo abelii ENSPPYG00000013028
132908 Pteropus vampyrus ENSPVAG00000004736 42254 Sorex araneus ENSSARG00000007166
9823 Sus scrofa ENSSSCG00000016059 37347 Tupaia belangeri ENSTBEG00000017692
99883 Tetraodon nigroviridis ENSTNIG00000017860 9478 Tarsius syrichta ENSTSYG00000001302
9739 Tursiops truncatus ENSTTRG00000001136 30538 Vicugna pacos ENSVPAG00000011545
8364 Xenopus tropicalis ENSXETG00000004662