
| Basic Information | |||
| Gene ID | 100173534 | ||
| Gene Name | SMAD5; MADH5 | ||
| Full Name | Mothers against decapentaplegic homolog 5 | ||
| Organism | Pongo abelii [9601] | ||
| Cross Reference | |||
| UniProt | Q5R6H7 | UniGene | Pab.11907 | 
| PDB | NULL | OMIM | NULL | 
| KEGG | pon:100173534 | UCSC | NULL | 
| Protein Interactions | |
| DIP | NULL | 
| IntAct | NULL | 
| MINT | NULL | 
| STRING | NULL | 
| Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID | 
| ENSEMBL | |||
| REFSEQ | 
| InterPro Annotation | |||||||
| Protein | Program | Term | IPRS | Start | End | Score | Description | 
| NP_001126544 | Gene3D | G3DSA:2.60.200.10 | IPR017855 | 263 | 465 | 6.50e-97 | SMAD domain-like | 
| NP_001126544 | Gene3D | G3DSA:3.90.520.10 | IPR013019 | 5 | 144 | 8.60e-62 | MAD homology, MH1 | 
| NP_001126544 | PANTHER | PTHR13703 | IPR013790 | 1 | 465 | 0.00e-00 | Dwarfin | 
| NP_001126544 | Pfam | PF03165 | IPR003619 | 32 | 132 | 4.80e-42 | MAD homology 1, Dwarfin-type | 
| NP_001126544 | Pfam | PF03166 | IPR001132 | 266 | 442 | 7.40e-78 | SMAD domain, Dwarfin-type | 
| NP_001126544 | ProSiteProfiles | PS51075 | IPR013019 | 13 | 137 | 0.00e-00 | MAD homology, MH1 | 
| NP_001126544 | ProSiteProfiles | PS51076 | IPR001132 | 271 | 465 | 0.00e-00 | SMAD domain, Dwarfin-type | 
| NP_001126544 | SMART | SM00523 | IPR003619 | 26 | 135 | 4.80e-71 | MAD homology 1, Dwarfin-type | 
| NP_001126544 | SMART | SM00524 | IPR001132 | 269 | 441 | 2.50e-108 | SMAD domain, Dwarfin-type | 
| NP_001126544 | SUPERFAMILY | SSF49879 | IPR008984 | 235 | 456 | 0.00e-00 | SMAD/FHA domain | 
| NP_001126544 | SUPERFAMILY | SSF56366 | IPR013019 | 14 | 132 | 0.00e-00 | MAD homology, MH1 | 
| Pfam Annotation | ||||
| Protein | Pfam ID | E.value | Name | Description | 
| NP_001126544 | PF03166 | 0 | MH2 | MH2 domain | 
| NP_001126544 | PF03165 | 2.29953e-42 | MH1 | MH1 domain | 
| NP_001126544 | PF10401 | 1.1e-06 | IRF-3 | Interferon-regulatory factor 3 | 
| Gene Ontology Annotation | |||
| Protein | Entry | Name Space | Description | 
| NP_001126544 | GO:0001657 | biological_process | ureteric bud development | 
| NP_001126544 | GO:0002051 | biological_process | osteoblast fate commitment | 
| NP_001126544 | GO:0006351 | biological_process | transcription, DNA-templated | 
| NP_001126544 | GO:0006468 | biological_process | protein phosphorylation | 
| NP_001126544 | GO:0007179 | biological_process | transforming growth factor beta receptor signaling pathway | 
| NP_001126544 | GO:0030509 | biological_process | BMP signaling pathway | 
| NP_001126544 | GO:0045669 | biological_process | positive regulation of osteoblast differentiation | 
| NP_001126544 | GO:0051216 | biological_process | cartilage development | 
| NP_001126544 | GO:0060348 | biological_process | bone development | 
| NP_001126544 | GO:0071773 | biological_process | cellular response to BMP stimulus | 
| NP_001126544 | GO:1901522 | biological_process | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | 
| NP_001126544 | GO:0005634 | cellular_component | nucleus | 
| NP_001126544 | GO:0005667 | cellular_component | transcription factor complex | 
| NP_001126544 | GO:0005737 | cellular_component | cytoplasm | 
| NP_001126544 | GO:0000979 | molecular_function | RNA polymerase II core promoter sequence-specific DNA binding | 
| NP_001126544 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity | 
| NP_001126544 | GO:0046872 | molecular_function | metal ion binding |