Basic Information
Gene ID 100551891
Gene Name EPAS1
Full Name Uncharacterized protein
Organism Anolis carolinensis [28377]

Cross Reference
UniProt H9G8J6 UniGene Acr.11765
PDB NULL OMIM NULL
KEGG acs:100551891 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003225226 Pfam PF08778 IPR014887 832 871 2.50e-19 HIF-1 alpha, transactivation domain, C-terminal
XP_003225226 Pfam PF11413 IPR021537 512 544 9.20e-18 Hypoxia-inducible factor, alpha subunit
XP_003225226 PRINTS PR00785 IPR001067 101 120 1.20e-06 Nuclear translocator
XP_003225226 PRINTS PR00785 IPR001067 242 259 1.20e-06 Nuclear translocator
XP_003225226 PRINTS PR00785 IPR001067 49 69 1.20e-06 Nuclear translocator
XP_003225226 ProSiteProfiles PS50112 IPR000014 248 299 0.00e-00 PAS domain
XP_003225226 ProSiteProfiles PS50112 IPR000014 92 147 0.00e-00 PAS domain
XP_003225226 ProSiteProfiles PS50888 IPR011598 14 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003225226 SMART SM00086 IPR001610 303 346 1.10e-11 PAC motif
XP_003225226 SMART SM00091 IPR000014 231 297 1.90e-10 PAS domain
XP_003225226 SMART SM00091 IPR000014 86 152 2.10e-11 PAS domain
XP_003225226 SMART SM00353 IPR011598 20 75 8.60e-12 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003225226 SUPERFAMILY SSF47459 IPR011598 11 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003225226 SUPERFAMILY SSF55785 IPR000014 243 345 0.00e-00 PAS domain
XP_003225226 SUPERFAMILY SSF55785 IPR000014 95 198 0.00e-00 PAS domain
XP_003225226 TIGRFAM TIGR00229 IPR000014 251 327 1.80e-07 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003225226 PF14598 2.7e-27 PAS_11 PAS domain
XP_003225226 PF08447 2.6e-25 PAS_3 PAS fold
XP_003225226 PF08778 9.8e-20 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
XP_003225226 PF11413 3e-18 HIF-1 Hypoxia-inducible factor-1
XP_003225226 PF00989 1.3e-13 PAS PAS fold
XP_003225226 PF13426 2.2e-11 PAS_9 PAS domain
XP_003225226 PF08448 2e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003225226 GO:0001666 biological_process response to hypoxia
XP_003225226 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_003225226 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
XP_003225226 GO:0071456 biological_process cellular response to hypoxia
XP_003225226 GO:0005634 cellular_component nucleus
XP_003225226 GO:0005737 cellular_component cytoplasm
XP_003225226 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003225226 GO:0004871 molecular_function signal transducer activity
XP_003225226 GO:0035035 molecular_function histone acetyltransferase binding