Basic Information
Gene ID 10379 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name IRF9; ISGF3G
Full Name Interferon regulatory factor 9
Organism Homo sapiens [9606]

Cross Reference
UniProt Q00978 UniGene Hs.1706
PDB NULL OMIM 147574
KEGG hsa:10379 UCSC uc001wmq.3

Protein Interactions
DIP NULL
IntAct Q00978
MINT MINT-1526689
STRING 9606.ENSP00000380073

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000380073 Gene3D G3DSA:1.10.10.10 IPR011991 11 118 8.40e-44 Winged helix-turn-helix DNA-binding domain
ENSP00000380073 Gene3D G3DSA:2.60.200.10 IPR017855 205 388 2.10e-50 SMAD domain-like
ENSP00000380073 Pfam PF00605 IPR001346 11 116 2.50e-43 Interferon regulatory factor DNA-binding domain
ENSP00000380073 Pfam PF10401 IPR019471 218 382 1.20e-42 Interferon regulatory factor-3
ENSP00000380073 PRINTS PR00267 IPR001346 11 30 8.00e-27 Interferon regulatory factor DNA-binding domain
ENSP00000380073 PRINTS PR00267 IPR001346 37 50 8.00e-27 Interferon regulatory factor DNA-binding domain
ENSP00000380073 PRINTS PR00267 IPR001346 55 72 8.00e-27 Interferon regulatory factor DNA-binding domain
ENSP00000380073 PRINTS PR00267 IPR001346 77 99 8.00e-27 Interferon regulatory factor DNA-binding domain
ENSP00000380073 ProSitePatterns PS00601 IPR019817 30 63 - Interferon regulatory factor, conserved site
ENSP00000380073 ProSiteProfiles PS51507 IPR001346 9 116 0.00e-00 Interferon regulatory factor DNA-binding domain
ENSP00000380073 SMART SM00348 IPR001346 5 117 2.30e-65 Interferon regulatory factor DNA-binding domain
ENSP00000380073 SUPERFAMILY SSF49879 IPR008984 208 390 0.00e-00 SMAD/FHA domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000380073 PF00605 1.59748e-43 IRF Interferon regulatory factor transcription factor
ENSP00000380073 PF10401 8.60397e-43 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000380073 GO:0005634 cellular_component nucleus
ENSP00000380073 GO:0000975 molecular_function regulatory region DNA binding
ENSP00000380073 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9103 Meleagris gallopavo 100542267 10029 Cricetulus griseus 100760392
9597 Pan paniscus 100973587 9555 Papio anubis 101020807
9595 Gorilla gorilla 101146951 13735 Pelodiscus sinensis 102455775
10224 Saccoglossus kowalevskii 100378859 61853 Nomascus leucogenys 100602600
8128 Oreochromis niloticus 100702346 39432 Saimiri boliviensis 101051991
9669 Mustela putorius furo 101689711 28377 Anolis carolinensis ENSACAG00000003946
9615 Canis familiaris ENSCAFG00000012007 7719 Ciona intestinalis ENSCING00000000808
51511 Ciona savignyi ENSCSAVG00000003970 9031 Gallus gallus ENSGALG00000005757
8049 Gadus morhua ENSGMOG00000002167 9785 Loxodonta africana ENSLAFG00000026182
59463 Myotis lucifugus ENSMLUG00000025255 13616 Monodelphis domestica ENSMODG00000003368
9978 Ochotona princeps ENSOPRG00000018909 9823 Sus scrofa ENSSSCG00000002002
59729 Taeniopygia guttata ENSTGUG00000006609 9739 Tursiops truncatus ENSTTRG00000008624
10090 Mus musculus 15900 7955 Danio rerio 403013
7668 Strongylocentrotus purpuratus 578336 9913 Bos taurus 614909
9544 Macaca mulatta 693933 9646 Ailuropoda melanoleuca ENSAMEG00000016347
9483 Callithrix jacchus ENSCJAG00000007065 10141 Cavia porcellus ENSCPOG00000026474
10020 Dipodomys ordii ENSDORG00000009268 9796 Equus caballus ENSECAG00000024429
9365 Erinaceus europaeus ENSEEUG00000002644 9371 Echinops telfairi ENSETEG00000018472
9685 Felis catus ENSFCAG00000018849 69293 Gasterosteus aculeatus ENSGACG00000015958
7897 Latimeria chalumnae ENSLACG00000004633 9315 Macropus eugenii ENSMEUG00000010784
9986 Oryctolagus cuniculus ENSOCUG00000028186 30611 Otolemur garnettii ENSOGAG00000026670
9813 Procavia capensis ENSPCAG00000015500 9601 Pongo abelii ENSPPYG00000007620
9598 Pan troglodytes ENSPTRG00000008435 132908 Pteropus vampyrus ENSPVAG00000007716
9305 Sarcophilus harrisii ENSSHAG00000001872 43179 Ictidomys tridecemlineatus ENSSTOG00000023450
37347 Tupaia belangeri ENSTBEG00000012240 99883 Tetraodon nigroviridis ENSTNIG00000009283
31033 Takifugu rubripes ENSTRUG00000017722 9478 Tarsius syrichta ENSTSYG00000007445
8364 Xenopus tropicalis ENSXETG00000011413 8083 Xiphophorus maculatus ENSXMAG00000004567