Basic Information
Gene ID 10419 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name PRMT5; HRMT1L5, IBP72, JBP1, SKB1
Full Name Protein arginine N-methyltransferase 5
Organism Homo sapiens [9606]

Cross Reference
UniProt O14744 UniGene Hs.367854
PDB 4GQB OMIM 604045
KEGG hsa:10419 UCSC uc001whm.1

Protein Interactions
DIP DIP-33172N
IntAct O14744
MINT MINT-1216859
STRING 9606.ENSP00000319169

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000319169 PANTHER PTHR10738 IPR007857 1 637 0.00e-00 Protein arginine N-methyltransferase PRMT5
ENSP00000319169 Pfam PF05185 IPR025799 183 618 1.20e-181 Protein arginine N-methyltransferase
ENSP00000319169 PIRSF PIRSF015894 IPR007857 1 637 0.00e-00 Protein arginine N-methyltransferase PRMT5
ENSP00000319169 ProSiteProfiles PS51678 IPR025799 308 615 0.00e-00 Protein arginine N-methyltransferase

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000319169 PF05185 0 PRMT5 PRMT5 arginine-N-methyltransferase

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000319169 GO:0000387 biological_process spliceosomal snRNP assembly
ENSP00000319169 GO:0006351 biological_process transcription, DNA-templated
ENSP00000319169 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000319169 GO:0018216 biological_process peptidyl-arginine methylation
ENSP00000319169 GO:0019918 biological_process peptidyl-arginine methylation, to symmetrical-dimethyl arginine
ENSP00000319169 GO:0042118 biological_process endothelial cell activation
ENSP00000319169 GO:0005634 cellular_component nucleus
ENSP00000319169 GO:0005737 cellular_component cytoplasm
ENSP00000319169 GO:0005829 cellular_component cytosol
ENSP00000319169 GO:0034709 cellular_component methylosome
ENSP00000319169 GO:0008168 molecular_function methyltransferase activity
ENSP00000319169 GO:0008469 molecular_function histone-arginine N-methyltransferase activity
ENSP00000319169 GO:0035243 molecular_function protein-arginine omega-N symmetric methyltransferase activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
132113 Bombus impatiens 100742212 8090 Oryzias latipes ENSORLG00000012353