Basic Information
Gene ID 11262 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name SP140; LYSP100
Full Name Nuclear body protein SP140
Organism Homo sapiens [9606]

Cross Reference
UniProt Q13342 UniGene Hs.632549
PDB 2MD8 OMIM 608602
KEGG hsa:11262 UCSC uc002vqn.3

Protein Interactions
DIP NULL
IntAct Q13342
MINT MINT-6631209
STRING 9606.ENSP00000375899

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000375899 Gene3D G3DSA:1.20.920.10 IPR001487 759 859 6.60e-16 Bromodomain
ENSP00000375899 Gene3D G3DSA:3.10.390.10 IPR010919 575 665 7.70e-37 SAND domain-like
ENSP00000375899 Gene3D G3DSA:3.30.40.10 IPR013083 674 746 9.40e-12 Zinc finger, RING/FYVE/PHD-type
ENSP00000375899 Pfam PF00439 IPR001487 794 836 8.80e-07 Bromodomain
ENSP00000375899 Pfam PF00628 IPR019787 693 735 1.20e-06 Zinc finger, PHD-finger
ENSP00000375899 Pfam PF01342 IPR000770 580 660 5.10e-30 SAND domain
ENSP00000375899 Pfam PF03172 IPR004865 37 138 1.10e-43 Sp100
ENSP00000375899 ProSitePatterns PS01359 IPR019786 693 733 - Zinc finger, PHD-type, conserved site
ENSP00000375899 ProSiteProfiles PS50014 IPR001487 795 829 0.00e-00 Bromodomain
ENSP00000375899 ProSiteProfiles PS50016 IPR019787 690 736 0.00e-00 Zinc finger, PHD-finger
ENSP00000375899 ProSiteProfiles PS50864 IPR000770 580 661 0.00e-00 SAND domain
ENSP00000375899 ProSiteProfiles PS51414 IPR004865 22 138 0.00e-00 Sp100
ENSP00000375899 SMART SM00249 IPR001965 692 734 6.30e-11 Zinc finger, PHD-type
ENSP00000375899 SMART SM00258 IPR000770 588 661 1.00e-48 SAND domain
ENSP00000375899 SMART SM00297 IPR001487 756 859 2.20e-23 Bromodomain
ENSP00000375899 SUPERFAMILY SSF47370 IPR001487 753 860 0.00e-00 Bromodomain
ENSP00000375899 SUPERFAMILY SSF57903 IPR011011 679 740 0.00e-00 Zinc finger, FYVE/PHD-type
ENSP00000375899 SUPERFAMILY SSF63763 IPR010919 575 665 0.00e-00 SAND domain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000375899 PF03172 6.44597e-44 Sp100 Sp100 domain
ENSP00000375899 PF01342 2.6e-30 SAND SAND domain
ENSP00000375899 PF00628 3.4e-07 PHD PHD-finger
ENSP00000375899 PF00439 3.5e-07 Bromodomain Bromodomain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000375899 GO:0005634 cellular_component nucleus
ENSP00000375899 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100978937 39432 Saimiri boliviensis 101048610
9555 Papio anubis 101010644 9646 Ailuropoda melanoleuca ENSAMEG00000016495
9483 Callithrix jacchus ENSCJAG00000013289 9785 Loxodonta africana ENSLAFG00000002303
61853 Nomascus leucogenys ENSNLEG00000013760 9823 Sus scrofa ENSSSCG00000016262
9913 Bos taurus ENSBTAG00000009664 10141 Cavia porcellus ENSCPOG00000010544
9595 Gorilla gorilla ENSGGOG00000006936 30608 Microcebus murinus ENSMICG00000015716
59463 Myotis lucifugus ENSMLUG00000001910 9544 Macaca mulatta ENSMMUG00000012199
9669 Mustela putorius furo ENSMPUG00000004415 30611 Otolemur garnettii ENSOGAG00000030726
9601 Pongo abelii ENSPPYG00000013253 9598 Pan troglodytes ENSPTRG00000013010
10116 Rattus norvegicus ENSRNOG00000022800 43179 Ictidomys tridecemlineatus ENSSTOG00000005247
9739 Tursiops truncatus ENSTTRG00000009293

Paralogs
93349