Basic Information
Gene ID 14634 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Gli3
Full Name Transcriptional activator GLI3
Organism Mus musculus [10090]

Cross Reference
UniProt Q61602 UniGene Mm.5098
PDB NULL OMIM NULL
KEGG mmu:14634 UCSC uc007pns.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10090.ENSMUSP00000106137

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000106137 Gene3D G3DSA:3.30.160.60 IPR013087 479 511 4.10e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000106137 Gene3D G3DSA:3.30.160.60 IPR013087 512 539 4.50e-06 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000106137 Gene3D G3DSA:3.30.160.60 IPR013087 540 574 1.00e-21 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000106137 Gene3D G3DSA:3.30.160.60 IPR013087 575 604 6.60e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000106137 Gene3D G3DSA:3.30.160.60 IPR013087 605 634 1.10e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSMUSP00000106137 Pfam PF00096 IPR007087 607 632 6.50e-04 Zinc finger, C2H2
ENSMUSP00000106137 ProSitePatterns PS00028 IPR007087 482 505 - Zinc finger, C2H2
ENSMUSP00000106137 ProSitePatterns PS00028 IPR007087 548 570 - Zinc finger, C2H2
ENSMUSP00000106137 ProSitePatterns PS00028 IPR007087 578 601 - Zinc finger, C2H2
ENSMUSP00000106137 ProSitePatterns PS00028 IPR007087 609 632 - Zinc finger, C2H2
ENSMUSP00000106137 ProSiteProfiles PS50157 IPR007087 480 512 0.00e-00 Zinc finger, C2H2
ENSMUSP00000106137 ProSiteProfiles PS50157 IPR007087 518 545 0.00e-00 Zinc finger, C2H2
ENSMUSP00000106137 ProSiteProfiles PS50157 IPR007087 546 575 0.00e-00 Zinc finger, C2H2
ENSMUSP00000106137 ProSiteProfiles PS50157 IPR007087 576 606 0.00e-00 Zinc finger, C2H2
ENSMUSP00000106137 ProSiteProfiles PS50157 IPR007087 607 637 0.00e-00 Zinc finger, C2H2
ENSMUSP00000106137 SMART SM00355 IPR015880 480 505 5.00e-04 Zinc finger, C2H2-like
ENSMUSP00000106137 SMART SM00355 IPR015880 513 540 4.10e-03 Zinc finger, C2H2-like
ENSMUSP00000106137 SMART SM00355 IPR015880 546 570 1.10e-05 Zinc finger, C2H2-like
ENSMUSP00000106137 SMART SM00355 IPR015880 576 601 1.40e-05 Zinc finger, C2H2-like
ENSMUSP00000106137 SMART SM00355 IPR015880 607 632 4.80e-07 Zinc finger, C2H2-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000106137 PF00096 8.4e-19 zf-C2H2 Zinc finger, C2H2 type
ENSMUSP00000106137 PF13465 3.3e-15 zf-H2C2_2 Zinc-finger double domain
ENSMUSP00000106137 PF13894 8.9e-08 zf-C2H2_4 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000106137 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000106137 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000106137 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMUSP00000106137 GO:0005634 cellular_component nucleus
ENSMUSP00000106137 GO:0005737 cellular_component cytoplasm
ENSMUSP00000106137 GO:0003677 molecular_function DNA binding
ENSMUSP00000106137 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000106137 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100575006 30195 Bombus terrestris 100649327
8128 Oreochromis niloticus 100707331 132113 Bombus impatiens 100746944
10029 Cricetulus griseus 100762738 143995 Megachile rotundata 100882254
9595 Gorilla gorilla 101153250 8083 Xiphophorus maculatus 102238290
13735 Pelodiscus sinensis 102458283 7425 Nasonia vitripennis 100118465
9986 Oryctolagus cuniculus 100355047 9646 Ailuropoda melanoleuca 100463969
9785 Loxodonta africana 100657131 7463 Apis florea 100869111
34638 Metaseiulus occidentalis 100907670 9597 Pan paniscus 100983700
9555 Papio anubis 101024392 39432 Saimiri boliviensis 101048440
9669 Mustela putorius furo 101680405 43179 Ictidomys tridecemlineatus 101977238
9031 Gallus gallus 420769 7227 Drosophila melanogaster 43767
7460 Apis mellifera 551746 7668 Strongylocentrotus purpuratus 580371
7070 Tribolium castaneum 658653 28377 Anolis carolinensis ENSACAG00000017547
9913 Bos taurus ENSBTAG00000010671 9615 Canis familiaris ENSCAFG00000004821
51511 Ciona savignyi ENSCSAVG00000009575 9361 Dasypus novemcinctus ENSDNOG00000008730
10020 Dipodomys ordii ENSDORG00000008299 9796 Equus caballus ENSECAG00000009281
9371 Echinops telfairi ENSETEG00000003955 9685 Felis catus ENSFCAG00000011989
8049 Gadus morhua ENSGMOG00000010335 7897 Latimeria chalumnae ENSLACG00000003758
9315 Macropus eugenii ENSMEUG00000013134 9103 Meleagris gallopavo ENSMGAG00000012277
59463 Myotis lucifugus ENSMLUG00000015711 61853 Nomascus leucogenys ENSNLEG00000003160
9258 Ornithorhynchus anatinus ENSOANG00000010699 9601 Pongo abelii ENSPPYG00000012778
9598 Pan troglodytes ENSPTRG00000019117 10116 Rattus norvegicus ENSRNOG00000014395
9305 Sarcophilus harrisii ENSSHAG00000004233 9823 Sus scrofa ENSSSCG00000015733
31033 Takifugu rubripes ENSTRUG00000007692 9739 Tursiops truncatus ENSTTRG00000003628
30538 Vicugna pacos ENSVPAG00000000048 9606 Homo sapiens 2736
9544 Macaca mulatta 702494 9358 Choloepus hoffmanni ENSCHOG00000003774
7719 Ciona intestinalis ENSCING00000012018 9483 Callithrix jacchus ENSCJAG00000003076
10141 Cavia porcellus ENSCPOG00000013233 7955 Danio rerio ENSDARG00000052131
9365 Erinaceus europaeus ENSEEUG00000011742 69293 Gasterosteus aculeatus ENSGACG00000004834
30608 Microcebus murinus ENSMICG00000010785 13616 Monodelphis domestica ENSMODG00000002714
30611 Otolemur garnettii ENSOGAG00000012651 9978 Ochotona princeps ENSOPRG00000011225
8090 Oryzias latipes ENSORLG00000012490 9813 Procavia capensis ENSPCAG00000015092
7757 Petromyzon marinus ENSPMAG00000007806 132908 Pteropus vampyrus ENSPVAG00000015920
37347 Tupaia belangeri ENSTBEG00000006673 59729 Taeniopygia guttata ENSTGUG00000001834
99883 Tetraodon nigroviridis ENSTNIG00000013668 9478 Tarsius syrichta ENSTSYG00000009406
8364 Xenopus tropicalis ENSXETG00000001856