Basic Information
Gene ID 17125 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Smad1; Madh1, Madr1
Full Name Mothers against decapentaplegic homolog 1
Organism Mus musculus [10090]

Cross Reference
UniProt P70340 UniGene Mm.223717
PDB 3KMP OMIM NULL
KEGG mmu:17125 UCSC uc009mip.2

Protein Interactions
DIP NULL
IntAct P70340
MINT MINT-99213
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_032565 Gene3D G3DSA:2.60.200.10 IPR017855 263 465 1.30e-97 SMAD domain-like
NP_032565 Gene3D G3DSA:3.90.520.10 IPR013019 5 144 2.30e-61 MAD homology, MH1
NP_032565 PANTHER PTHR13703 IPR013790 1 465 0.00e-00 Dwarfin
NP_032565 Pfam PF03165 IPR003619 31 131 4.60e-42 MAD homology 1, Dwarfin-type
NP_032565 Pfam PF03166 IPR001132 266 442 3.10e-78 SMAD domain, Dwarfin-type
NP_032565 ProSiteProfiles PS51075 IPR013019 12 136 0.00e-00 MAD homology, MH1
NP_032565 ProSiteProfiles PS51076 IPR001132 271 465 0.00e-00 SMAD domain, Dwarfin-type
NP_032565 SMART SM00523 IPR003619 25 134 1.50e-70 MAD homology 1, Dwarfin-type
NP_032565 SMART SM00524 IPR001132 269 441 5.70e-110 SMAD domain, Dwarfin-type
NP_032565 SUPERFAMILY SSF49879 IPR008984 221 456 0.00e-00 SMAD/FHA domain
NP_032565 SUPERFAMILY SSF56366 IPR013019 13 131 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_032565 PF03166 0 MH2 MH2 domain
NP_032565 PF03165 1.69978e-42 MH1 MH1 domain
NP_032565 PF10401 7.2e-07 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
NP_032565 GO:0001657 biological_process ureteric bud development
NP_032565 GO:0002051 biological_process osteoblast fate commitment
NP_032565 GO:0006351 biological_process transcription, DNA-templated
NP_032565 GO:0006468 biological_process protein phosphorylation
NP_032565 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
NP_032565 GO:0030509 biological_process BMP signaling pathway
NP_032565 GO:0045669 biological_process positive regulation of osteoblast differentiation
NP_032565 GO:0051216 biological_process cartilage development
NP_032565 GO:0060348 biological_process bone development
NP_032565 GO:0071773 biological_process cellular response to BMP stimulus
NP_032565 GO:1901522 biological_process positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
NP_032565 GO:0005634 cellular_component nucleus
NP_032565 GO:0005667 cellular_component transcription factor complex
NP_032565 GO:0005737 cellular_component cytoplasm
NP_032565 GO:0000979 molecular_function RNA polymerase II core promoter sequence-specific DNA binding
NP_032565 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_032565 GO:0046872 molecular_function metal ion binding