Basic Information
Gene ID 22807 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name IKZF2; HELIOS, ZNFN1A2
Full Name Zinc finger protein Helios
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9UKS7 UniGene Hs.604950
PDB NULL OMIM 606234
KEGG hsa:22807 UCSC uc002vel.3

Protein Interactions
DIP NULL
IntAct Q9UKS7
MINT NULL
STRING 9606.ENSP00000410447

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000342876 Gene3D G3DSA:3.30.160.60 IPR013087 119 147 1.20e-08 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000342876 Gene3D G3DSA:3.30.160.60 IPR013087 148 167 9.60e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000342876 Gene3D G3DSA:3.30.160.60 IPR013087 168 193 1.40e-10 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000342876 Gene3D G3DSA:3.30.160.60 IPR013087 194 221 1.80e-06 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000342876 ProSitePatterns PS00028 IPR007087 120 140 - Zinc finger, C2H2
ENSP00000342876 ProSitePatterns PS00028 IPR007087 148 168 - Zinc finger, C2H2
ENSP00000342876 ProSitePatterns PS00028 IPR007087 176 196 - Zinc finger, C2H2
ENSP00000342876 ProSitePatterns PS00028 IPR007087 204 225 - Zinc finger, C2H2
ENSP00000342876 ProSitePatterns PS00028 IPR007087 479 499 - Zinc finger, C2H2
ENSP00000342876 ProSiteProfiles PS50157 IPR007087 118 145 0.00e-00 Zinc finger, C2H2
ENSP00000342876 ProSiteProfiles PS50157 IPR007087 146 173 0.00e-00 Zinc finger, C2H2
ENSP00000342876 ProSiteProfiles PS50157 IPR007087 174 201 0.00e-00 Zinc finger, C2H2
ENSP00000342876 ProSiteProfiles PS50157 IPR007087 202 230 0.00e-00 Zinc finger, C2H2
ENSP00000342876 SMART SM00355 IPR015880 118 140 2.60e-04 Zinc finger, C2H2-like
ENSP00000342876 SMART SM00355 IPR015880 146 168 5.80e-07 Zinc finger, C2H2-like
ENSP00000342876 SMART SM00355 IPR015880 174 196 1.30e-06 Zinc finger, C2H2-like
ENSP00000342876 SMART SM00355 IPR015880 202 225 1.20e-04 Zinc finger, C2H2-like
ENSP00000342876 SMART SM00355 IPR015880 477 499 3.20e-02 Zinc finger, C2H2-like
ENSP00000342876 SMART SM00355 IPR015880 505 529 2.10e-03 Zinc finger, C2H2-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000342876 PF13465 3.8e-22 zf-H2C2_2 Zinc-finger double domain
ENSP00000342876 PF00096 1e-15 zf-C2H2 Zinc finger, C2H2 type
ENSP00000342876 PF13894 1.1e-09 zf-C2H2_4 C2H2-type zinc finger

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000342876 GO:0006351 biological_process transcription, DNA-templated
ENSP00000342876 GO:0005634 cellular_component nucleus
ENSP00000342876 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100403694 9103 Meleagris gallopavo 100538840
9785 Loxodonta africana 100669350 10029 Cricetulus griseus 100760184
9597 Pan paniscus 100968912 9555 Papio anubis 100999509
39432 Saimiri boliviensis 101048828 31033 Takifugu rubripes 101067835
9595 Gorilla gorilla 101132867 10090 Mus musculus 22779
10141 Cavia porcellus ENSCPOG00000013506 51511 Ciona savignyi ENSCSAVG00000002773
9685 Felis catus ENSFCAG00000009654 9031 Gallus gallus 395309
9615 Canis familiaris 488510 28377 Anolis carolinensis ENSACAG00000025864
9646 Ailuropoda melanoleuca ENSAMEG00000008058 9913 Bos taurus ENSBTAG00000037804
9358 Choloepus hoffmanni ENSCHOG00000002669 7719 Ciona intestinalis ENSCING00000006863
7955 Danio rerio ENSDARG00000013539 9361 Dasypus novemcinctus ENSDNOG00000000179
10020 Dipodomys ordii ENSDORG00000007539 9796 Equus caballus ENSECAG00000000040
9365 Erinaceus europaeus ENSEEUG00000001089 9371 Echinops telfairi ENSETEG00000019814
69293 Gasterosteus aculeatus ENSGACG00000003033 8049 Gadus morhua ENSGMOG00000000522
7897 Latimeria chalumnae ENSLACG00000015293 9315 Macropus eugenii ENSMEUG00000000683
30608 Microcebus murinus ENSMICG00000013862 59463 Myotis lucifugus ENSMLUG00000012494
9544 Macaca mulatta ENSMMUG00000000381 9669 Mustela putorius furo ENSMPUG00000007839
9258 Ornithorhynchus anatinus ENSOANG00000009330 9986 Oryctolagus cuniculus ENSOCUG00000007309
30611 Otolemur garnettii ENSOGAG00000016680 8128 Oreochromis niloticus ENSONIG00000004211
9978 Ochotona princeps ENSOPRG00000005789 8090 Oryzias latipes ENSORLG00000016031
9813 Procavia capensis ENSPCAG00000005974 9601 Pongo abelii ENSPPYG00000013139
13735 Pelodiscus sinensis ENSPSIG00000014940 9598 Pan troglodytes ENSPTRG00000012884
132908 Pteropus vampyrus ENSPVAG00000014197 42254 Sorex araneus ENSSARG00000012607
9305 Sarcophilus harrisii ENSSHAG00000001687 9823 Sus scrofa ENSSSCG00000016164
43179 Ictidomys tridecemlineatus ENSSTOG00000011683 37347 Tupaia belangeri ENSTBEG00000010122
59729 Taeniopygia guttata ENSTGUG00000007910 99883 Tetraodon nigroviridis ENSTNIG00000016437
9478 Tarsius syrichta ENSTSYG00000006472 9739 Tursiops truncatus ENSTTRG00000007440
30538 Vicugna pacos ENSVPAG00000004262 8364 Xenopus tropicalis ENSXETG00000003127
8083 Xiphophorus maculatus ENSXMAG00000008077