Basic Information
Gene ID 2304 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOXE1; FKHL15, FOXE2, TITF2, TTF2
Full Name Forkhead box protein E1
Organism Homo sapiens [9606]

Cross Reference
UniProt O00358 UniGene Hs.159234
PDB NULL OMIM 602617
KEGG hsa:2304 UCSC uc004axu.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000364265

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000364265 Gene3D G3DSA:1.10.10.10 IPR011991 48 139 2.00e-38 Winged helix-turn-helix DNA-binding domain
ENSP00000364265 Pfam PF00250 IPR001766 53 148 1.40e-41 Transcription factor, fork head
ENSP00000364265 PRINTS PR00053 IPR001766 53 66 7.70e-23 Transcription factor, fork head
ENSP00000364265 PRINTS PR00053 IPR001766 74 91 7.70e-23 Transcription factor, fork head
ENSP00000364265 PRINTS PR00053 IPR001766 97 114 7.70e-23 Transcription factor, fork head
ENSP00000364265 ProSitePatterns PS00657 IPR018122 53 66 - Transcription factor, fork head, conserved site
ENSP00000364265 ProSitePatterns PS00658 IPR018122 97 103 - Transcription factor, fork head, conserved site
ENSP00000364265 ProSiteProfiles PS50039 IPR001766 53 147 0.00e-00 Transcription factor, fork head
ENSP00000364265 SMART SM00339 IPR001766 51 141 7.10e-62 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000364265 PF00250 1.10002e-41 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000364265 GO:0006351 biological_process transcription, DNA-templated
ENSP00000364265 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000364265 GO:0005634 cellular_component nucleus
ENSP00000364265 GO:0003677 molecular_function DNA binding
ENSP00000364265 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000364265 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8364 Xenopus tropicalis 100038190 10224 Saccoglossus kowalevskii 100303469
8128 Oreochromis niloticus 100702474 9597 Pan paniscus 100969767
9555 Papio anubis 101022981 10090 Mus musculus 110805
8049 Gadus morhua ENSGMOG00000016511 7897 Latimeria chalumnae ENSLACG00000012261
9785 Loxodonta africana ENSLAFG00000018265 9103 Meleagris gallopavo ENSMGAG00000010792
8090 Oryzias latipes ENSORLG00000007101 9598 Pan troglodytes ENSPTRG00000029193
7955 Danio rerio 567676 28377 Anolis carolinensis ENSACAG00000009553
9483 Callithrix jacchus ENSCJAG00000010918 51511 Ciona savignyi ENSCSAVG00000000553
69293 Gasterosteus aculeatus ENSGACG00000017386 9031 Gallus gallus ENSGALG00000028153
9595 Gorilla gorilla ENSGGOG00000003735 9315 Macropus eugenii ENSMEUG00000016591
30608 Microcebus murinus ENSMICG00000012741 59463 Myotis lucifugus ENSMLUG00000002064
13616 Monodelphis domestica ENSMODG00000003217 9986 Oryctolagus cuniculus ENSOCUG00000022454
13735 Pelodiscus sinensis ENSPSIG00000009611 9305 Sarcophilus harrisii ENSSHAG00000016533
99883 Tetraodon nigroviridis ENSTNIG00000011038 31033 Takifugu rubripes ENSTRUG00000010676
9478 Tarsius syrichta ENSTSYG00000009045 30538 Vicugna pacos ENSVPAG00000010542
8083 Xiphophorus maculatus ENSXMAG00000020182

Paralogs
2301