Basic Information
Gene ID 23462 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name HEY1; BHLHB31, CHF2, HERP2, HESR1, HRT1
Full Name Hairy/enhancer-of-split related with YRPW motif protein 1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9Y5J3 UniGene Hs.234434
PDB 2DB7 OMIM 602953
KEGG hsa:23462 UCSC uc003ybm.3

Protein Interactions
DIP NULL
IntAct Q9Y5J3
MINT MINT-1179634
STRING 9606.ENSP00000338272

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000338272 Gene3D G3DSA:4.10.280.10 IPR011598 50 110 1.10e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000338272 Pfam PF00010 IPR011598 53 108 1.60e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000338272 Pfam PF07527 IPR003650 126 168 1.70e-12 Orange
ENSP00000338272 ProSiteProfiles PS50888 IPR011598 49 108 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000338272 ProSiteProfiles PS51054 IPR003650 126 162 0.00e-00 Orange
ENSP00000338272 SMART SM00353 IPR011598 55 114 3.60e-16 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000338272 SMART SM00511 IPR018352 124 171 1.10e-16 Orange subgroup
ENSP00000338272 SUPERFAMILY SSF47459 IPR011598 50 127 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000338272 PF00010 8.9e-17 HLH Helix-loop-helix DNA-binding domain
ENSP00000338272 PF07527 7.1e-13 Hairy_orange Hairy Orange

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000338272 GO:0007219 biological_process Notch signaling pathway
ENSP00000338272 GO:0005634 cellular_component nucleus
ENSP00000338272 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100119662 7029 Acyrthosiphon pisum 100169375
10224 Saccoglossus kowalevskii 100303559 7460 Apis mellifera 100577069
30195 Bombus terrestris 100648331 9785 Loxodonta africana 100657428
8128 Oreochromis niloticus 100711035 132113 Bombus impatiens 100744110
10029 Cricetulus griseus 100755611 143995 Megachile rotundata 100877455
34638 Metaseiulus occidentalis 100900811 9305 Sarcophilus harrisii 100918295
9555 Papio anubis 101005751 31033 Takifugu rubripes 101068985
9669 Mustela putorius furo 101691308 43179 Ictidomys tridecemlineatus 101964079
7897 Latimeria chalumnae 102352589 10090 Mus musculus 15213
400682 Amphimedon queenslandica 100640672 7463 Apis florea 100869544
9597 Pan paniscus 100984313 39432 Saimiri boliviensis 101047640
9685 Felis catus 101085436 7070 Tribolium castaneum 656543
9646 Ailuropoda melanoleuca ENSAMEG00000017517 9615 Canis familiaris ENSCAFG00000008391
9365 Erinaceus europaeus ENSEEUG00000008612 69293 Gasterosteus aculeatus ENSGACG00000003436
8049 Gadus morhua ENSGMOG00000017811 9315 Macropus eugenii ENSMEUG00000009781
13616 Monodelphis domestica ENSMODG00000017653 9978 Ochotona princeps ENSOPRG00000003055
9813 Procavia capensis ENSPCAG00000006105 9598 Pan troglodytes ENSPTRG00000020364
132908 Pteropus vampyrus ENSPVAG00000009503 59729 Taeniopygia guttata ENSTGUG00000011633
9739 Tursiops truncatus ENSTTRG00000000086 7227 Drosophila melanogaster 35764
9913 Bos taurus 408005 7668 Strongylocentrotus purpuratus 578414
7955 Danio rerio 58146 9544 Macaca mulatta 712988
28377 Anolis carolinensis ENSACAG00000013410 9358 Choloepus hoffmanni ENSCHOG00000002389
7719 Ciona intestinalis ENSCING00000006427 9483 Callithrix jacchus ENSCJAG00000000477
10141 Cavia porcellus ENSCPOG00000021417 9361 Dasypus novemcinctus ENSDNOG00000010392
10020 Dipodomys ordii ENSDORG00000009655 9796 Equus caballus ENSECAG00000017010
9371 Echinops telfairi ENSETEG00000009764 9031 Gallus gallus ENSGALG00000027364
9595 Gorilla gorilla ENSGGOG00000009960 9103 Meleagris gallopavo ENSMGAG00000011620
30608 Microcebus murinus ENSMICG00000001913 59463 Myotis lucifugus ENSMLUG00000009035
61853 Nomascus leucogenys ENSNLEG00000002239 9258 Ornithorhynchus anatinus ENSOANG00000000812
9986 Oryctolagus cuniculus ENSOCUG00000016568 8090 Oryzias latipes ENSORLG00000012953
9601 Pongo abelii ENSPPYG00000018693 13735 Pelodiscus sinensis ENSPSIG00000003791
10116 Rattus norvegicus ENSRNOG00000011593 42254 Sorex araneus ENSSARG00000011755
37347 Tupaia belangeri ENSTBEG00000010367 99883 Tetraodon nigroviridis ENSTNIG00000017785
30538 Vicugna pacos ENSVPAG00000002300 8364 Xenopus tropicalis ENSXETG00000007864
8083 Xiphophorus maculatus ENSXMAG00000003593