Basic Information
Gene ID 27022 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name FOXD3; HFH2
Full Name Forkhead box protein D3
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9UJU5 UniGene Hs.546573
PDB NULL OMIM 611539
KEGG hsa:27022 UCSC uc001dax.2

Protein Interactions
DIP NULL
IntAct Q9UJU5
MINT NULL
STRING 9606.ENSP00000360157

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000360157 Gene3D G3DSA:1.10.10.10 IPR011991 133 227 4.40e-40 Winged helix-turn-helix DNA-binding domain
ENSP00000360157 Pfam PF00250 IPR001766 141 236 1.30e-42 Transcription factor, fork head
ENSP00000360157 PRINTS PR00053 IPR001766 141 154 6.90e-23 Transcription factor, fork head
ENSP00000360157 PRINTS PR00053 IPR001766 162 179 6.90e-23 Transcription factor, fork head
ENSP00000360157 PRINTS PR00053 IPR001766 185 202 6.90e-23 Transcription factor, fork head
ENSP00000360157 ProSitePatterns PS00657 IPR018122 141 154 - Transcription factor, fork head, conserved site
ENSP00000360157 ProSitePatterns PS00658 IPR018122 185 191 - Transcription factor, fork head, conserved site
ENSP00000360157 ProSiteProfiles PS50039 IPR001766 141 235 0.00e-00 Transcription factor, fork head
ENSP00000360157 SMART SM00339 IPR001766 139 229 3.40e-63 Transcription factor, fork head

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000360157 PF00250 8.39378e-43 Fork_head Fork head domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000360157 GO:0006351 biological_process transcription, DNA-templated
ENSP00000360157 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000360157 GO:0005634 cellular_component nucleus
ENSP00000360157 GO:0003677 molecular_function DNA binding
ENSP00000360157 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000360157 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100114412 7029 Acyrthosiphon pisum 100167072
8090 Oryzias latipes 100301607 10224 Saccoglossus kowalevskii 100329067
8128 Oreochromis niloticus 100692011 132113 Bombus impatiens 100745558
143995 Megachile rotundata 100881718 34638 Metaseiulus occidentalis 100908613
9555 Papio anubis 100998316 6239 Caenorhabditis elegans 174721
30195 Bombus terrestris 100650001 31033 Takifugu rubripes 101077701
9598 Pan troglodytes 456905 9913 Bos taurus 532383
9544 Macaca mulatta 696085 28377 Anolis carolinensis ENSACAG00000022097
7719 Ciona intestinalis ENSCING00000023594 51511 Ciona savignyi ENSCSAVG00000003964
8049 Gadus morhua ENSGMOG00000018243 59463 Myotis lucifugus ENSMLUG00000006018
7227 Drosophila melanogaster 37631 8364 Xenopus tropicalis 496851
7668 Strongylocentrotus purpuratus 751845 9615 Canis familiaris ENSCAFG00000023383
7955 Danio rerio ENSDARG00000021032 9361 Dasypus novemcinctus ENSDNOG00000005013
69293 Gasterosteus aculeatus ENSGACG00000006933 9595 Gorilla gorilla ENSGGOG00000027326
9785 Loxodonta africana ENSLAFG00000003874 9258 Ornithorhynchus anatinus ENSOANG00000011490
13735 Pelodiscus sinensis ENSPSIG00000010073 10116 Rattus norvegicus ENSRNOG00000009021
43179 Ictidomys tridecemlineatus ENSSTOG00000023664 8083 Xiphophorus maculatus ENSXMAG00000002170

Paralogs
200350 ENSG00000251493 349334