Basic Information
Gene ID 27244 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name SESN1; PA26, SEST1
Full Name Sestrin-1
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9Y6P5 UniGene Hs.591336
PDB NULL OMIM 606103
KEGG hsa:27244 UCSC uc003psu.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000306734

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000393762 PANTHER PTHR12474 IPR006730 1 551 0.00e-00 PA26 p53-induced protein (sestrin)
ENSP00000393762 Pfam PF04636 IPR006730 105 551 6.80e-224 PA26 p53-induced protein (sestrin)

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000393762 PF04636 0 PA26 PA26 p53-induced protein (sestrin)
ENSP00000393762 PF02627 0.00083 CMD Carboxymuconolactone decarboxylase family

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000393762 GO:0007050 biological_process cell cycle arrest
ENSP00000393762 GO:0005634 cellular_component nucleus

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100770597 9595 Gorilla gorilla 101124847
43179 Ictidomys tridecemlineatus 101959724 59463 Myotis lucifugus 102438956
9597 Pan paniscus 100974358 9555 Papio anubis 101021354
39432 Saimiri boliviensis 101041032 9685 Felis catus 101099380
9669 Mustela putorius furo 101685090 8083 Xiphophorus maculatus 102216498
9598 Pan troglodytes 462922 9913 Bos taurus 538226
9031 Gallus gallus ENSGALG00000015286 9315 Macropus eugenii ENSMEUG00000003436
9103 Meleagris gallopavo ENSMGAG00000013478 13616 Monodelphis domestica ENSMODG00000017990
8128 Oreochromis niloticus ENSONIG00000013301 8090 Oryzias latipes ENSORLG00000013484
9601 Pongo abelii ENSPPYG00000016900 132908 Pteropus vampyrus ENSPVAG00000000611
9823 Sus scrofa ENSSSCG00000004390 59729 Taeniopygia guttata ENSTGUG00000012113
99883 Tetraodon nigroviridis ENSTNIG00000012277 31033 Takifugu rubripes ENSTRUG00000001205
9478 Tarsius syrichta ENSTSYG00000004141 30538 Vicugna pacos ENSVPAG00000000819
10141 Cavia porcellus ENSCPOG00000013793 8049 Gadus morhua ENSGMOG00000005675
7897 Latimeria chalumnae ENSLACG00000017259 9258 Ornithorhynchus anatinus ENSOANG00000015028
9305 Sarcophilus harrisii ENSSHAG00000002079 9739 Tursiops truncatus ENSTTRG00000004173