Basic Information
Gene ID 281993
Gene Name PPARG; NR1C3
Full Name Peroxisome proliferator-activated receptor gamma
Organism Bos taurus [9913]

Cross Reference
UniProt O18971 UniGene Bt.3862
PDB NULL OMIM NULL
KEGG bta:281993 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_851367 Gene3D G3DSA:1.10.565.10 IPR008946 192 222 1.20e-75 Nuclear hormone receptor, ligand-binding
NP_851367 Gene3D G3DSA:1.10.565.10 IPR008946 278 502 1.20e-75 Nuclear hormone receptor, ligand-binding
NP_851367 Gene3D G3DSA:3.30.50.10 IPR013088 139 191 2.20e-24 Zinc finger, NHR/GATA-type
NP_851367 Pfam PF00104 IPR000536 320 484 9.40e-31 Nuclear hormone receptor, ligand-binding, core
NP_851367 Pfam PF00105 IPR001628 138 204 2.70e-27 Zinc finger, nuclear hormone receptor-type
NP_851367 Pfam PF12577 IPR022590 31 108 1.70e-32 Peroxisome proliferator-activated receptor gamma, N-terminal
NP_851367 PRINTS PR00047 IPR001628 139 155 6.00e-19 Zinc finger, nuclear hormone receptor-type
NP_851367 PRINTS PR00047 IPR001628 155 170 6.00e-19 Zinc finger, nuclear hormone receptor-type
NP_851367 PRINTS PR00047 IPR001628 187 195 6.00e-19 Zinc finger, nuclear hormone receptor-type
NP_851367 PRINTS PR00047 IPR001628 195 203 6.00e-19 Zinc finger, nuclear hormone receptor-type
NP_851367 PRINTS PR00398 IPR001723 199 209 7.30e-28 Steroid hormone receptor
NP_851367 PRINTS PR00398 IPR001723 316 337 7.30e-28 Steroid hormone receptor
NP_851367 PRINTS PR00398 IPR001723 337 353 7.30e-28 Steroid hormone receptor
NP_851367 PRINTS PR00398 IPR001723 405 420 7.30e-28 Steroid hormone receptor
NP_851367 PRINTS PR00398 IPR001723 462 479 7.30e-28 Steroid hormone receptor
NP_851367 PRINTS PR01288 IPR003074 228 242 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01288 IPR003074 242 261 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01288 IPR003074 355 368 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01288 IPR003074 372 387 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01288 IPR003074 390 403 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01288 IPR003074 452 469 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01288 IPR003074 486 498 4.10e-64 Peroxisome proliferator-activated receptor
NP_851367 PRINTS PR01291 IPR003077 103 121 2.80e-54 Peroxisome proliferator-activated receptor, gamma
NP_851367 PRINTS PR01291 IPR003077 215 231 2.80e-54 Peroxisome proliferator-activated receptor, gamma
NP_851367 PRINTS PR01291 IPR003077 42 56 2.80e-54 Peroxisome proliferator-activated receptor, gamma
NP_851367 PRINTS PR01291 IPR003077 439 452 2.80e-54 Peroxisome proliferator-activated receptor, gamma
NP_851367 PRINTS PR01291 IPR003077 60 73 2.80e-54 Peroxisome proliferator-activated receptor, gamma
NP_851367 PRINTS PR01291 IPR003077 85 102 2.80e-54 Peroxisome proliferator-activated receptor, gamma
NP_851367 ProSitePatterns PS00031 IPR001628 139 165 - Zinc finger, nuclear hormone receptor-type
NP_851367 ProSiteProfiles PS51030 IPR001628 136 210 0.00e-00 Zinc finger, nuclear hormone receptor-type
NP_851367 SMART SM00399 IPR001628 136 206 8.50e-37 Zinc finger, nuclear hormone receptor-type
NP_851367 SMART SM00430 IPR000536 315 474 6.30e-30 Nuclear hormone receptor, ligand-binding, core
NP_851367 SUPERFAMILY SSF48508 IPR008946 240 503 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_851367 PF12577 7e-33 PPARgamma_N PPAR gamma N-terminal region
NP_851367 PF00104 4.4e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
NP_851367 PF00105 1.7e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
NP_851367 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
NP_851367 GO:0001890 biological_process placenta development
NP_851367 GO:0006355 biological_process regulation of transcription, DNA-templated
NP_851367 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
NP_851367 GO:0008217 biological_process regulation of blood pressure
NP_851367 GO:0010871 biological_process negative regulation of receptor biosynthetic process
NP_851367 GO:0010887 biological_process negative regulation of cholesterol storage
NP_851367 GO:0010891 biological_process negative regulation of sequestering of triglyceride
NP_851367 GO:0015909 biological_process long-chain fatty acid transport
NP_851367 GO:0030224 biological_process monocyte differentiation
NP_851367 GO:0030855 biological_process epithelial cell differentiation
NP_851367 GO:0032526 biological_process response to retinoic acid
NP_851367 GO:0032869 biological_process cellular response to insulin stimulus
NP_851367 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
NP_851367 GO:0042593 biological_process glucose homeostasis
NP_851367 GO:0042953 biological_process lipoprotein transport
NP_851367 GO:0045165 biological_process cell fate commitment
NP_851367 GO:0045600 biological_process positive regulation of fat cell differentiation
NP_851367 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
NP_851367 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
NP_851367 GO:0048469 biological_process cell maturation
NP_851367 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
NP_851367 GO:0050872 biological_process white fat cell differentiation
NP_851367 GO:0050873 biological_process brown fat cell differentiation
NP_851367 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
NP_851367 GO:0055098 biological_process response to low-density lipoprotein particle
NP_851367 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
NP_851367 GO:0071285 biological_process cellular response to lithium ion
NP_851367 GO:0005634 cellular_component nucleus
NP_851367 GO:0005829 cellular_component cytosol
NP_851367 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
NP_851367 GO:0003677 molecular_function DNA binding
NP_851367 GO:0003682 molecular_function chromatin binding
NP_851367 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_851367 GO:0003707 molecular_function steroid hormone receptor activity
NP_851367 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
NP_851367 GO:0008144 molecular_function drug binding
NP_851367 GO:0008270 molecular_function zinc ion binding
NP_851367 GO:0019899 molecular_function enzyme binding
NP_851367 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
NP_851367 GO:0033613 molecular_function activating transcription factor binding
NP_851367 GO:0043565 molecular_function sequence-specific DNA binding
NP_851367 GO:0046965 molecular_function retinoid X receptor binding