Basic Information
Gene ID 284459 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name HKR1; ZNF875
Full Name Krueppel-related zinc finger protein 1
Organism Homo sapiens [9606]

Cross Reference
UniProt P10072 UniGene Hs.729090
PDB NULL OMIM 165250
KEGG hsa:284459 UCSC uc002ogc.3

Protein Interactions
DIP NULL
IntAct P10072
MINT NULL
STRING 9606.ENSP00000315505

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 272 302 1.40e-07 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 303 330 8.80e-19 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 331 358 6.00e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 359 385 1.10e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 386 404 2.80e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 405 432 1.70e-16 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 433 460 1.70e-18 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 461 488 3.60e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 489 516 3.00e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 517 544 1.50e-15 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 545 577 1.70e-13 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 579 607 4.80e-10 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 608 626 1.20e-13 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Gene3D G3DSA:3.30.160.60 IPR013087 627 659 7.60e-17 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000315505 Pfam PF00096 IPR007087 579 601 1.80e-02 Zinc finger, C2H2
ENSP00000315505 Pfam PF00096 IPR007087 607 629 7.20e-06 Zinc finger, C2H2
ENSP00000315505 Pfam PF00096 IPR007087 635 657 6.00e-07 Zinc finger, C2H2
ENSP00000315505 Pfam PF01352 IPR001909 33 73 5.90e-22 Krueppel-associated box
ENSP00000315505 ProSitePatterns PS00028 IPR007087 303 323 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 331 351 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 359 379 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 387 407 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 415 435 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 443 463 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 471 491 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 499 519 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 527 547 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 555 575 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 581 601 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 609 629 - Zinc finger, C2H2
ENSP00000315505 ProSitePatterns PS00028 IPR007087 637 657 - Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 301 328 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 329 356 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 357 384 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 385 412 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 413 440 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 441 468 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 469 496 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 497 524 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 525 552 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 553 577 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 579 606 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 607 634 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50157 IPR007087 635 659 0.00e-00 Zinc finger, C2H2
ENSP00000315505 ProSiteProfiles PS50805 IPR001909 33 104 0.00e-00 Krueppel-associated box
ENSP00000315505 SMART SM00349 IPR001909 33 93 9.70e-36 Krueppel-associated box
ENSP00000315505 SMART SM00355 IPR015880 301 323 1.00e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 329 351 1.60e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 357 379 4.10e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 385 407 6.80e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 413 435 3.50e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 441 463 5.70e-07 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 469 491 1.30e-05 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 497 519 2.20e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 525 547 5.30e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 553 575 4.60e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 579 601 9.80e-05 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 607 629 7.70e-06 Zinc finger, C2H2-like
ENSP00000315505 SMART SM00355 IPR015880 635 657 4.80e-07 Zinc finger, C2H2-like
ENSP00000315505 SUPERFAMILY SSF109640 IPR001909 31 89 0.00e-00 Krueppel-associated box

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000315505 PF00096 0 zf-C2H2 Zinc finger, C2H2 type
ENSP00000315505 PF13465 0 zf-H2C2_2 Zinc-finger double domain
ENSP00000315505 PF13894 1.5e-34 zf-C2H2_4 C2H2-type zinc finger
ENSP00000315505 PF01352 2.2e-22 KRAB KRAB box
ENSP00000315505 PF13912 3.2e-19 zf-C2H2_6 C2H2-type zinc finger
ENSP00000315505 PF12171 3.4e-12 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding
ENSP00000315505 PF13451 4.5e-05 zf-trcl Probable zinc-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000315505 GO:0006351 biological_process transcription, DNA-templated
ENSP00000315505 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000315505 GO:0005634 cellular_component nucleus
ENSP00000315505 GO:0003677 molecular_function DNA binding
ENSP00000315505 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101008733 39432 Saimiri boliviensis 101042725
9595 Gorilla gorilla 101126761 9615 Canis familiaris 484542
9358 Choloepus hoffmanni ENSCHOG00000001271 10020 Dipodomys ordii ENSDORG00000013277
9796 Equus caballus ENSECAG00000010313 30608 Microcebus murinus ENSMICG00000010166
9669 Mustela putorius furo ENSMPUG00000017853 30611 Otolemur garnettii ENSOGAG00000015925
9813 Procavia capensis ENSPCAG00000008046 9601 Pongo abelii ENSPPYG00000009912
9598 Pan troglodytes ENSPTRG00000010907 42254 Sorex araneus ENSSARG00000010899
9478 Tarsius syrichta ENSTSYG00000003011 9739 Tursiops truncatus ENSTTRG00000013782
30538 Vicugna pacos ENSVPAG00000004909