Basic Information
Gene ID 321364
Gene Name id2b
Full Name Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, b
Organism Danio rerio [7955]

Cross Reference
UniProt Q6PBJ0 UniGene Dr.76468
PDB NULL OMIM NULL
KEGG dre:321364 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7955.ENSDARP00000048758

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000108958 Gene3D G3DSA:4.10.280.10 IPR011598 36 84 5.50e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000108958 PANTHER PTHR11723 IPR026052 2 130 0.00e-00 DNA-binding protein inhibitor
ENSDARP00000108958 Pfam PF00010 IPR011598 35 74 2.20e-12 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000108958 ProSiteProfiles PS50888 IPR011598 21 73 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000108958 SMART SM00353 IPR011598 26 79 4.10e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSDARP00000108958 SUPERFAMILY SSF47459 IPR011598 36 87 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000108958 PF00010 1.5e-12 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000108958 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSDARP00000108958 GO:0007275 biological_process multicellular organismal development
ENSDARP00000108958 GO:0010628 biological_process positive regulation of gene expression
ENSDARP00000108958 GO:0010629 biological_process negative regulation of gene expression
ENSDARP00000108958 GO:0033598 biological_process mammary gland epithelial cell proliferation
ENSDARP00000108958 GO:0045665 biological_process negative regulation of neuron differentiation
ENSDARP00000108958 GO:0045777 biological_process positive regulation of blood pressure
ENSDARP00000108958 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSDARP00000108958 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSDARP00000108958 GO:0048557 biological_process embryonic digestive tract morphogenesis
ENSDARP00000108958 GO:0048661 biological_process positive regulation of smooth muscle cell proliferation
ENSDARP00000108958 GO:0048663 biological_process neuron fate commitment
ENSDARP00000108958 GO:0060749 biological_process mammary gland alveolus development
ENSDARP00000108958 GO:0061030 biological_process epithelial cell differentiation involved in mammary gland alveolus development
ENSDARP00000108958 GO:0061031 biological_process endodermal digestive tract morphogenesis
ENSDARP00000108958 GO:0071158 biological_process positive regulation of cell cycle arrest
ENSDARP00000108958 GO:0090398 biological_process cellular senescence
ENSDARP00000108958 GO:2000178 biological_process negative regulation of neural precursor cell proliferation
ENSDARP00000108958 GO:0005634 cellular_component nucleus
ENSDARP00000108958 GO:0005737 cellular_component cytoplasm
ENSDARP00000108958 GO:0043234 cellular_component protein complex
ENSDARP00000108958 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100028188 9796 Equus caballus 100057240
9601 Pongo abelii 100172180 59729 Taeniopygia guttata 100224948
28377 Anolis carolinensis 100560759 61853 Nomascus leucogenys 100584179
9785 Loxodonta africana 100662671 10029 Cricetulus griseus 100769110
9555 Papio anubis 101017423 39432 Saimiri boliviensis 101052660
9685 Felis catus 101090256 9595 Gorilla gorilla 101149541
8090 Oryzias latipes 101169826 9669 Mustela putorius furo 101673045
8083 Xiphophorus maculatus 102223896 7897 Latimeria chalumnae 102364478
13735 Pelodiscus sinensis 102456718 10116 Rattus norvegicus 25587
9597 Pan paniscus 100985375 31033 Takifugu rubripes 101073580
43179 Ictidomys tridecemlineatus 101967190 9606 Homo sapiens 3398
9913 Bos taurus 538690 10020 Dipodomys ordii ENSDORG00000014815
59463 Myotis lucifugus ENSMLUG00000008563 9258 Ornithorhynchus anatinus ENSOANG00000012166
8128 Oreochromis niloticus ENSONIG00000003666 9813 Procavia capensis ENSPCAG00000005885
132908 Pteropus vampyrus ENSPVAG00000003912 9478 Tarsius syrichta ENSTSYG00000001685
9598 Pan troglodytes 745532 9615 Canis familiaris ENSCAFG00000013269
9358 Choloepus hoffmanni ENSCHOG00000003078 9483 Callithrix jacchus ENSCJAG00000006037
9365 Erinaceus europaeus ENSEEUG00000007814 9371 Echinops telfairi ENSETEG00000014219
69293 Gasterosteus aculeatus ENSGACG00000009030 8049 Gadus morhua ENSGMOG00000010271
9315 Macropus eugenii ENSMEUG00000008206 9103 Meleagris gallopavo ENSMGAG00000007767
30608 Microcebus murinus ENSMICG00000010061 9544 Macaca mulatta ENSMMUG00000003237
9986 Oryctolagus cuniculus ENSOCUG00000024446 9978 Ochotona princeps ENSOPRG00000003784
42254 Sorex araneus ENSSARG00000003385 37347 Tupaia belangeri ENSTBEG00000012464
99883 Tetraodon nigroviridis ENSTNIG00000017308 9739 Tursiops truncatus ENSTTRG00000008691
8364 Xenopus tropicalis ENSXETG00000008272