Basic Information
Gene ID 321622
Gene Name hmgb1a; HMGB1, hmgb1
Full Name High-mobility group box 1
Organism Danio rerio [7955]

Cross Reference
UniProt Q6NX86 UniGene Dr.158952
PDB NULL OMIM NULL
KEGG dre:321622 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 7955.ENSDARP00000102600

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
NP_955849 Gene3D G3DSA:1.10.30.10 IPR009071 7 77 1.40e-28 High mobility group box domain
NP_955849 Gene3D G3DSA:1.10.30.10 IPR009071 92 166 1.10e-30 High mobility group box domain
NP_955849 Pfam PF00505 IPR009071 94 162 3.40e-27 High mobility group box domain
NP_955849 Pfam PF09011 IPR009071 5 77 1.20e-26 High mobility group box domain
NP_955849 ProSitePatterns PS00353 IPR017967 40 51 - HMG box A DNA-binding domain, conserved site
NP_955849 ProSiteProfiles PS50118 IPR009071 8 78 0.00e-00 High mobility group box domain
NP_955849 ProSiteProfiles PS50118 IPR009071 94 162 0.00e-00 High mobility group box domain
NP_955849 SMART SM00398 IPR009071 7 79 5.40e-27 High mobility group box domain
NP_955849 SMART SM00398 IPR009071 93 163 2.80e-32 High mobility group box domain
NP_955849 SUPERFAMILY SSF47095 IPR009071 3 80 0.00e-00 High mobility group box domain
NP_955849 SUPERFAMILY SSF47095 IPR009071 78 162 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
NP_955849 PF09011 4.2039e-45 HMG_box_2 HMG-box domain
NP_955849 PF00505 8.1976e-43 HMG_box HMG (high mobility group) box
NP_955849 PF14887 0.00014 HMG_box_5 HMG (high mobility group) box 5

Gene Ontology Annotation
Protein Entry Name Space Description
NP_955849 GO:0002437 biological_process inflammatory response to antigenic stimulus
NP_955849 GO:0006288 biological_process base-excision repair, DNA ligation
NP_955849 GO:0017055 biological_process negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
NP_955849 GO:0033151 biological_process V(D)J recombination
NP_955849 GO:0043065 biological_process positive regulation of apoptotic process
NP_955849 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
NP_955849 GO:0043388 biological_process positive regulation of DNA binding
NP_955849 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
NP_955849 GO:0000793 cellular_component condensed chromosome
NP_955849 GO:0005615 cellular_component extracellular space
NP_955849 GO:0005634 cellular_component nucleus
NP_955849 GO:0005694 cellular_component chromosome
NP_955849 GO:0009986 cellular_component cell surface
NP_955849 GO:0017053 cellular_component transcriptional repressor complex
NP_955849 GO:0003677 molecular_function DNA binding
NP_955849 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
NP_955849 GO:0070491 molecular_function repressing transcription factor binding