Basic Information | |||
Gene ID | 321622 | ||
Gene Name | hmgb1a; HMGB1, hmgb1 | ||
Full Name | High-mobility group box 1 | ||
Organism | Danio rerio [7955] |
Cross Reference | |||
UniProt | Q6NX86 | UniGene | Dr.158952 |
PDB | NULL | OMIM | NULL |
KEGG | dre:321622 | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | 7955.ENSDARP00000102600 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
NP_955849 | Gene3D | G3DSA:1.10.30.10 | IPR009071 | 7 | 77 | 1.40e-28 | High mobility group box domain |
NP_955849 | Gene3D | G3DSA:1.10.30.10 | IPR009071 | 92 | 166 | 1.10e-30 | High mobility group box domain |
NP_955849 | Pfam | PF00505 | IPR009071 | 94 | 162 | 3.40e-27 | High mobility group box domain |
NP_955849 | Pfam | PF09011 | IPR009071 | 5 | 77 | 1.20e-26 | High mobility group box domain |
NP_955849 | ProSitePatterns | PS00353 | IPR017967 | 40 | 51 | - | HMG box A DNA-binding domain, conserved site |
NP_955849 | ProSiteProfiles | PS50118 | IPR009071 | 8 | 78 | 0.00e-00 | High mobility group box domain |
NP_955849 | ProSiteProfiles | PS50118 | IPR009071 | 94 | 162 | 0.00e-00 | High mobility group box domain |
NP_955849 | SMART | SM00398 | IPR009071 | 7 | 79 | 5.40e-27 | High mobility group box domain |
NP_955849 | SMART | SM00398 | IPR009071 | 93 | 163 | 2.80e-32 | High mobility group box domain |
NP_955849 | SUPERFAMILY | SSF47095 | IPR009071 | 3 | 80 | 0.00e-00 | High mobility group box domain |
NP_955849 | SUPERFAMILY | SSF47095 | IPR009071 | 78 | 162 | 0.00e-00 | High mobility group box domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
NP_955849 | PF09011 | 4.2039e-45 | HMG_box_2 | HMG-box domain |
NP_955849 | PF00505 | 8.1976e-43 | HMG_box | HMG (high mobility group) box |
NP_955849 | PF14887 | 0.00014 | HMG_box_5 | HMG (high mobility group) box 5 |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
NP_955849 | GO:0002437 | biological_process | inflammatory response to antigenic stimulus |
NP_955849 | GO:0006288 | biological_process | base-excision repair, DNA ligation |
NP_955849 | GO:0017055 | biological_process | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly |
NP_955849 | GO:0033151 | biological_process | V(D)J recombination |
NP_955849 | GO:0043065 | biological_process | positive regulation of apoptotic process |
NP_955849 | GO:0043280 | biological_process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
NP_955849 | GO:0043388 | biological_process | positive regulation of DNA binding |
NP_955849 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
NP_955849 | GO:0000793 | cellular_component | condensed chromosome |
NP_955849 | GO:0005615 | cellular_component | extracellular space |
NP_955849 | GO:0005634 | cellular_component | nucleus |
NP_955849 | GO:0005694 | cellular_component | chromosome |
NP_955849 | GO:0009986 | cellular_component | cell surface |
NP_955849 | GO:0017053 | cellular_component | transcriptional repressor complex |
NP_955849 | GO:0003677 | molecular_function | DNA binding |
NP_955849 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
NP_955849 | GO:0070491 | molecular_function | repressing transcription factor binding |