Basic Information
Gene ID 403639
Gene Name ESR2
Full Name Uncharacterized protein
Organism Canis familiaris [9615]

Cross Reference
UniProt F1Q2H9 UniGene Cfa.166
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCAFP00000023305 Gene3D G3DSA:1.10.565.10 IPR008946 222 517 3.50e-80 Nuclear hormone receptor, ligand-binding
ENSCAFP00000023305 Gene3D G3DSA:3.30.50.10 IPR013088 168 221 6.30e-28 Zinc finger, NHR/GATA-type
ENSCAFP00000023305 Pfam PF00104 IPR000536 303 494 1.90e-33 Nuclear hormone receptor, ligand-binding, core
ENSCAFP00000023305 Pfam PF00105 IPR001628 167 235 3.80e-31 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 Pfam PF12497 IPR021064 31 142 1.90e-36 Estrogen receptor beta, N-terminal
ENSCAFP00000023305 PIRSF PIRSF002527 IPR024178 42 549 3.40e-295 Oestrogen receptor/oestrogen-related receptor
ENSCAFP00000023305 PIRSF PIRSF500102 IPR028355 3 549 0.00e-00 Estrogen receptor beta/gamma
ENSCAFP00000023305 PRINTS PR00047 IPR001628 168 184 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 PRINTS PR00047 IPR001628 184 199 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 PRINTS PR00047 IPR001628 217 225 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 PRINTS PR00047 IPR001628 225 233 5.90e-17 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 PRINTS PR00398 IPR001723 229 239 3.30e-23 Steroid hormone receptor
ENSCAFP00000023305 PRINTS PR00398 IPR001723 320 341 3.30e-23 Steroid hormone receptor
ENSCAFP00000023305 PRINTS PR00398 IPR001723 341 357 3.30e-23 Steroid hormone receptor
ENSCAFP00000023305 PRINTS PR00398 IPR001723 409 424 3.30e-23 Steroid hormone receptor
ENSCAFP00000023305 PRINTS PR00398 IPR001723 476 493 3.30e-23 Steroid hormone receptor
ENSCAFP00000023305 ProSitePatterns PS00031 IPR001628 168 194 - Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 ProSiteProfiles PS51030 IPR001628 165 240 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 SMART SM00399 IPR001628 165 236 5.90e-37 Zinc finger, nuclear hormone receptor-type
ENSCAFP00000023305 SMART SM00430 IPR000536 319 488 1.90e-35 Nuclear hormone receptor, ligand-binding, core
ENSCAFP00000023305 SUPERFAMILY SSF48508 IPR008946 217 230 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSCAFP00000023305 SUPERFAMILY SSF48508 IPR008946 272 518 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCAFP00000023305 PF12497 9e-37 ERbeta_N Estrogen receptor beta
ENSCAFP00000023305 PF00104 1.2e-33 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSCAFP00000023305 PF00105 1.8e-31 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCAFP00000023305 GO:0006351 biological_process transcription, DNA-templated
ENSCAFP00000023305 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSCAFP00000023305 GO:0030520 biological_process intracellular estrogen receptor signaling pathway
ENSCAFP00000023305 GO:0005634 cellular_component nucleus
ENSCAFP00000023305 GO:0003677 molecular_function DNA binding
ENSCAFP00000023305 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCAFP00000023305 GO:0003707 molecular_function steroid hormone receptor activity
ENSCAFP00000023305 GO:0005496 molecular_function steroid binding
ENSCAFP00000023305 GO:0008270 molecular_function zinc ion binding
ENSCAFP00000023305 GO:0030284 molecular_function estrogen receptor activity
ENSCAFP00000023305 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100033964 9555 Papio anubis 100303418
9601 Pongo abelii 100459579 10029 Cricetulus griseus 100763291
30611 Otolemur garnettii 100946964 9597 Pan paniscus 100988122
39432 Saimiri boliviensis 101046392 8083 Xiphophorus maculatus 102232037
7897 Latimeria chalumnae 102366308 13735 Pelodiscus sinensis 102447875
10090 Mus musculus 13983 7955 Danio rerio 317734
9544 Macaca mulatta 574110 9358 Choloepus hoffmanni ENSCHOG00000012987
9483 Callithrix jacchus ENSCJAG00000019502 10141 Cavia porcellus ENSCPOG00000005703
9361 Dasypus novemcinctus ENSDNOG00000013868 9365 Erinaceus europaeus ENSEEUG00000006141
9371 Echinops telfairi ENSETEG00000014544 9685 Felis catus ENSFCAG00000009636
69293 Gasterosteus aculeatus ENSGACG00000007514 9031 Gallus gallus ENSGALG00000011801
9595 Gorilla gorilla ENSGGOG00000003030 8049 Gadus morhua ENSGMOG00000019003
9785 Loxodonta africana ENSLAFG00000017799 9315 Macropus eugenii ENSMEUG00000008494
30608 Microcebus murinus ENSMICG00000013003 13616 Monodelphis domestica ENSMODG00000009240
9258 Ornithorhynchus anatinus ENSOANG00000009109 8128 Oreochromis niloticus ENSONIG00000005633
9978 Ochotona princeps ENSOPRG00000005700 8090 Oryzias latipes ENSORLG00000018012
9813 Procavia capensis ENSPCAG00000011157 7757 Petromyzon marinus ENSPMAG00000008530
132908 Pteropus vampyrus ENSPVAG00000017577 10116 Rattus norvegicus ENSRNOG00000005343
42254 Sorex araneus ENSSARG00000004498 9305 Sarcophilus harrisii ENSSHAG00000008174
43179 Ictidomys tridecemlineatus ENSSTOG00000015102 37347 Tupaia belangeri ENSTBEG00000001569
99883 Tetraodon nigroviridis ENSTNIG00000003064 31033 Takifugu rubripes ENSTRUG00000013709
30538 Vicugna pacos ENSVPAG00000004869 8364 Xenopus tropicalis ENSXETG00000007257
9598 Pan troglodytes 452964 9646 Ailuropoda melanoleuca ENSAMEG00000003956
9103 Meleagris gallopavo ENSMGAG00000013507 59463 Myotis lucifugus ENSMLUG00000011894
9669 Mustela putorius furo ENSMPUG00000006688 9823 Sus scrofa ENSSSCG00000005109
9478 Tarsius syrichta ENSTSYG00000009621 9739 Tursiops truncatus ENSTTRG00000000517