Basic Information | |||
Gene ID | 4091 ; ![]() ![]() | ||
Gene Name | SMAD6; MADH6 | ||
Full Name | Mothers against decapentaplegic homolog 6 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | O43541 | UniGene | Hs.153863 |
PDB | NULL | OMIM | 614823 |
KEGG | hsa:4091 | UCSC | uc002aqg.3 |
Protein Interactions | |
DIP | DIP-36708N |
IntAct | O43541 |
MINT | MINT-1198639 |
STRING | 9606.ENSP00000288840 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000288840 | Gene3D | G3DSA:2.60.200.10 | IPR017855 | 325 | 495 | 1.30e-60 | SMAD domain-like |
ENSP00000288840 | Gene3D | G3DSA:3.90.520.10 | IPR013019 | 1 | 27 | 1.20e-53 | MAD homology, MH1 |
ENSP00000288840 | Gene3D | G3DSA:3.90.520.10 | IPR013019 | 171 | 282 | 1.20e-53 | MAD homology, MH1 |
ENSP00000288840 | PANTHER | PTHR13703 | IPR013790 | 1 | 496 | 0.00e-00 | Dwarfin |
ENSP00000288840 | Pfam | PF03165 | IPR003619 | 173 | 270 | 5.00e-27 | MAD homology 1, Dwarfin-type |
ENSP00000288840 | Pfam | PF03166 | IPR001132 | 327 | 495 | 1.90e-54 | SMAD domain, Dwarfin-type |
ENSP00000288840 | ProSiteProfiles | PS51075 | IPR013019 | 148 | 275 | 0.00e-00 | MAD homology, MH1 |
ENSP00000288840 | ProSiteProfiles | PS51076 | IPR001132 | 331 | 496 | 0.00e-00 | SMAD domain, Dwarfin-type |
ENSP00000288840 | SMART | SM00523 | IPR003619 | 167 | 273 | 7.00e-54 | MAD homology 1, Dwarfin-type |
ENSP00000288840 | SMART | SM00524 | IPR001132 | 329 | 493 | 1.00e-90 | SMAD domain, Dwarfin-type |
ENSP00000288840 | SUPERFAMILY | SSF49879 | IPR008984 | 319 | 495 | 0.00e-00 | SMAD/FHA domain |
ENSP00000288840 | SUPERFAMILY | SSF56366 | IPR013019 | 169 | 270 | 0.00e-00 | MAD homology, MH1 |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000288840 | PF03166 | 0 | MH2 | MH2 domain |
ENSP00000288840 | PF03165 | 3.1e-27 | MH1 | MH1 domain |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
30195 | Bombus terrestris | 100642241 | 9785 | Loxodonta africana | 100668483 |
8128 | Oreochromis niloticus | 100695008 | 10029 | Cricetulus griseus | 100758934 |
30611 | Otolemur garnettii | 100961390 | 9597 | Pan paniscus | 100992268 |
9555 | Papio anubis | 101015947 | 39432 | Saimiri boliviensis | 101035055 |
7897 | Latimeria chalumnae | 102355681 | 8364 | Xenopus tropicalis | 100038072 |
9823 | Sus scrofa | 100152069 | 7029 | Acyrthosiphon pisum | 100169367 |
10224 | Saccoglossus kowalevskii | 100303485 | 28377 | Anolis carolinensis | 100561979 |
132113 | Bombus impatiens | 100742914 | 7463 | Apis florea | 100865353 |
143995 | Megachile rotundata | 100880401 | 31033 | Takifugu rubripes | 101064248 |
9669 | Mustela putorius furo | 101678479 | 8083 | Xiphophorus maculatus | 102217868 |
7227 | Drosophila melanogaster | 42059 | 9913 | Bos taurus | 511279 |
7955 | Danio rerio | 564395 | 7070 | Tribolium castaneum | 658331 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000003315 | 9483 | Callithrix jacchus | ENSCJAG00000007573 |
10141 | Cavia porcellus | ENSCPOG00000001535 | 9361 | Dasypus novemcinctus | ENSDNOG00000008227 |
9796 | Equus caballus | ENSECAG00000013706 | 9371 | Echinops telfairi | ENSETEG00000006896 |
9685 | Felis catus | ENSFCAG00000012300 | 69293 | Gasterosteus aculeatus | ENSGACG00000005085 |
9031 | Gallus gallus | ENSGALG00000025898 | 9595 | Gorilla gorilla | ENSGGOG00000013002 |
8049 | Gadus morhua | ENSGMOG00000008363 | 9315 | Macropus eugenii | ENSMEUG00000009103 |
9103 | Meleagris gallopavo | ENSMGAG00000009875 | 30608 | Microcebus murinus | ENSMICG00000001554 |
9544 | Macaca mulatta | ENSMMUG00000019018 | 61853 | Nomascus leucogenys | ENSNLEG00000012971 |
9258 | Ornithorhynchus anatinus | ENSOANG00000013559 | 9978 | Ochotona princeps | ENSOPRG00000014974 |
8090 | Oryzias latipes | ENSORLG00000006825 | 9813 | Procavia capensis | ENSPCAG00000004267 |
7757 | Petromyzon marinus | ENSPMAG00000008281 | 9601 | Pongo abelii | ENSPPYG00000006581 |
132908 | Pteropus vampyrus | ENSPVAG00000001721 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000000696 |
59729 | Taeniopygia guttata | ENSTGUG00000009467 | 99883 | Tetraodon nigroviridis | ENSTNIG00000009545 |
9739 | Tursiops truncatus | ENSTTRG00000010237 | 7460 | Apis mellifera | 413371 |
7668 | Strongylocentrotus purpuratus | 593676 | 9986 | Oryctolagus cuniculus | ENSOCUG00000006134 |
10116 | Rattus norvegicus | ENSRNOG00000009173 | 9305 | Sarcophilus harrisii | ENSSHAG00000007962 |
37347 | Tupaia belangeri | ENSTBEG00000001301 |